Results 71 to 80 of about 689,309 (95)

Viral vector-mediated RNA interference in the retina [PDF]

open access: yes, 2010
RNA interference (RNAi) is a highly conserved post-transcriptional gene silencing process triggered by double-stranded RNA (dsRNA) in eukaryotic cells.
Georgiadis, A.
core  

Clinicopathological correlation of retinal pigment epithelial tears in exudative age related macular degeneration: pretear, tear, and scarred tear.

open access: yes, 2001
To analyse the histopathology of vascularised pigment epithelial detachments and tears of the retinal pigment epithelium (RPE) in age related macular degeneration (AMD)
JONESCU-CUYPERS, CP   +9 more
core   +1 more source

Treatment of retinal pigment epithelial detachment with antiangiogenic therapy

open access: yes, 2010
Luis AriasDepartment of Ophthalmology, Bellvitge University Hospital, Barcelona, SpainPurpose: Evaluate the efficacy of pegaptanib, a selective anti-vascular endothelial growth factor (VEGF) agent, and bevacizumab, a nonselective anti-VEGF agent, for ...
Luis Arias
core  

Efficient downregulation of VEGF in retinal pigment epithelial cells by integrin ligand-labeled liposome-mediated siRNA delivery

open access: yes, 2013
Cheng-Wei Chen,1 Ming-Kung Yeh,2 Chia-Yang Shiau,3 Chiao-Hsi Chiang,4,* Da-Wen Lu5,*1Chengwei Biotechnology Co, Ltd, 2Bureau of Pharmaceutical Affairs, Military of National Defense Medical Affairs Bureau, 3Graduate Institute of Medical Sciences, 4School ...
Chiang C, Shiau C, Lu D, Chen C, Yeh M
core  

Retinal pigment epithelial tear following intravitreal bevacizumab for choroidal neovascular membrane due to age-related macular degeneration

open access: yes, 2007
Retinal pigment epithelium (RPE) tears are an uncommon but visually damaging complication of pigment epithelial detachment (PED), caused by weak atrophic margins of chronic PED and contraction of sub-RPE fibrovascular scar tissue.
Hannan, S.R.   +11 more
core   +1 more source

Transscleral drainage to treat peripheral exudative hemorrhagic chorioretinopathy caused by retinal pigment epithelial hemorrhage

open access: yes
Purpose: To report a case of peripheral exudative hemorrhagic chorioretinopathy with hemorrhagic retinal detachment and subretinal pigment epithelial hemorrhage treated with transscleral subretinal fluid drainage.
Isao Saito   +3 more
core   +1 more source

Biomaterial templates for the culture and transplantation of retinal pigment epithelial cells: A critical review

open access: yes, 2016
The idea of retinal cell transplantation as a potential treatment for age-related retinal degeneration, a leading cause of blindness in the Western world, has been around for a number of decades. To date, however, it has not been entirely successful; one
F.K. Chen   +9 more
core   +1 more source

Spontaneous rip of the retinal pigment epithelium with a macular hole in neovascular age-related aacular degeneration

open access: yes, 2019
Purpose To report a case of retinal pigment epithelial tear associated with a macular hole in a patient with neovascular age-related macular degeneration (AMD). Design Observational case report.
Emerson, Geoffrey G., Ghazi, Nicola G.
core   +1 more source

Association of drusen deposition with choroidal intercapillary pillars in the aging human eye [PDF]

open access: yes, 2004
PURPOSE. To determine the pattern of drusen accumulation with age and to investigate the initial sites of deposition and their relationship to choroidal capillaries in human donor eyes from the eye bank of Moorfields Eye Hospital.METHODS.
Al Hosaini, H   +5 more
core  

Evaluation of ultraviolet light toxicity on cultured retinal pigment epithelial and retinal ganglion cells

open access: yes, 2010
Sankarathi Balaiya, Ravi K Murthy, Vikram S Brar, Kakarla V ChalamDepartment of Ophthalmology, University of Florida College of Medicine, Jacksonville, FL, USAPurpose: Our study is aimed at evaluating the role of UVB light in inducing ...
Sankarathi Balaiya   +3 more
core  

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