Results 91 to 100 of about 66,016 (272)

Epinephrine, but not dexamethasone, induces apoptosis in human retinal pigment epithelium cells in vitro: Possible implications on the pathogenesis of central serous chorioretinopathy

Philippine Journal of Ophthalmology, 2004
Objective: The pathogenesis of central serous chorioretinopathy is poorly understood. It is believed to be due to dysfunction of the retinal pigment epithelium and/or choroid, and has been associated with elevated levels of epinephrine and administration
Santiago Antonio B. Sibayan, MD, PhD, Karin Kobuch, MD, Detlev Spiegel, MD, Elfriede Eckert, MTA, Rita Leser, MTA, Jan Monzer, PhD, Veit-Peter Gabel, MD   +6 more
doaj  

Retinal findings in membranoproliferative glomerulonephritis

American Journal of Ophthalmology Case Reports, 2017
Purpose: To assess the evolution of retinal findings in patients with membranoproliferative glomerulonephritis (MPGN) by funduscopy, intravenous fluorescein angiography and optical coherence tomography. Observations: Three women and one man were followed
Ahmad M. Mansour, Luiz H. Lima, J. Fernando Arevalo, Miguel Hage Amaro, Virginia Lozano, Alaa Bou Ghannam, Errol W. Chan   +6 more
doaj   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

JAPANESE QUAIL (COTURNIX JAPONICA) AS THE MODEL OF HUMAN AGING RETINAL PROCESSES. REPORT № 2. COMPARATIVE ANALYSIS OF THE COMPOSITION OF RETINOIDS ISOLATED FROM RETINAL PIGMENT EPITHELIUM OF HUMAN AND JAPANESE QUAIL EYES

Офтальмохирургия, 2015
Purpose. To compare the composition of retinoids of lipofuscin granules (LG) isolated from retinal pigment epithelium (RPE) of human cadaver eyes and Japanese quail. Material and methods.
M. A. Yakovleva, A. V. Zykova, P. M. Arbuhanova, N. N. Trofimova, S. A. Borzenok, M. A. Ostrovsky, P. P. Zak   +6 more
doaj  

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Characterisation of neural progenitors from the adult retina and ciliary epithelium

, 2009
The mammalian central neural retina (CNR) lacks the capability to regenerate, a phenomenon retained by lower vertebrates. However, retinal stem cells have been isolated from the ciliary epithelium of the mammalian retina.
Kokkinopoulos, I.
core  

Extraocular Photoreception in Optic Lobes, Suckers, and Skin of Octopus vulgaris

Integrative Zoology, EarlyView.
Evidence of extra‐ocular photoreception in Octopus vulgaris (a) Diagram of the O. vulgaris different tissues considered: SPB, sucker proximal big; SPL, sucker proximal large; SM, sucker medium; SD, sucker distal; SK, skin; OL, optic lobes; RT, retina; (b‐d) Gene expression analysis of Ov‐GRK1 (red), Ov‐retinochrome (green), Ov‐rhodopsin (blue) mRNA ...
Valeria Maselli, Al‐Sayed Al‐Soudy, Mariangela Norcia, Stefania Galdiero, Sara Palladino, Emanuela Cirillo, Gianluca Polese, Anna Di Cosmo   +7 more
wiley   +1 more source

Japanese quail (Coturnix japonica) as the model of human aging retinal processes. Report № 2. Comparative analysis of the composition of retinoids isolated from retinal pigment epithelium of human and Japanese quail eyes

Офтальмохирургия, 2013
Purpose. To compare the composition of retinoids of lipofuscin granules (LG) isolated from retinal pigment epithelium (RPE) of human cadaver eyes and Japanese quail. Material and methods. The Japanese quail′s retina and retinal pigment epithelium
M.A. Yakovleva, A.V. Zykova, P.M. Arbuhanova, N.N. Trofimova, S.A. Borzenok, M.A. Ostrovsky, P.P. Zak   +6 more
doaj  

Mesopic microperimetry in Stargardt disease: Application and reliability

Acta Ophthalmologica, EarlyView.
Abstract Purpose Mesopic microperimetry (mMP) is a promising functional endpoint in clinical trials for Stargardt disease type 1 (STGD1). This study evaluated the test–retest variability of mMP and influencing factors, which is essential for ensuring reliability in future STGD1 trials.
Sybren H. Kootstra, Jeroen A. A. H. Pas, Patty P. A. Dhooge, Steffen Schmitz‐Valckenberg, Maurizio Battaglia Parodi, Philipp Herrmann, Frank G. Holz, Andrew J. Lotery, Katarina Stingl, Thomas H. Wheeler‐Schilling, Camiel J. F. Boon, Carel B. Hoyng, Soraprazan Consortium   +12 more
wiley   +1 more source

Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo.

PLoS ONE, 2016
The accumulation of N-retinylidene-N-retinylethanolamine (A2E, a toxic by-product of the visual pigment cycle) in the retinal pigment epithelium (RPE) is a major cause of visual impairment in the elderly.
Valérie Fontaine, Elodie Monteiro, Elena Brazhnikova, Laëtitia Lesage, Christine Balducci, Louis Guibout, Laurence Feraille, Pierre-Paul Elena, José-Alain Sahel, Stanislas Veillet, René Lafont   +10 more
doaj   +1 more source