Results 141 to 150 of about 283,262 (306)
The effect of rhegmatogenous retinal detachment on retinal oxygenation
Abstract Purpose Little is known about the effects of retinal detachment on oxygen extraction from retinal vessels. The role of oxygen supply from the retinal vessels in a detached area has not previously been investigated in vivo in humans. Retinal oximetry is a non‐invasive measurement of retinal oxygen saturation.
Anne‐Sofie Petri +8 more
wiley +1 more source
Visual pigments have a conserved phenylalanine in transmembrane helix 5 located near the β-ionone ring of the retinal chromophore. Site-directed mutants of this residue (F207) in a short-wavelength sensitive visual pigment (VCOP) were studied using UV ...
Barry E. Knox (187574) +3 more
core +1 more source
Radial outer retina reflectivity (RORR) sign in LAMP2‐associated retinopathy
Abstract Purpose To describe the radial outer retina reflectivity (RORR) sign in patients carrying pathogenic variants in the X‐linked lysosome‐associated membrane protein‐2 (LAMP2) gene and to review the histologic characteristics of LAMP2 expression in the human retina.
Rachael C. Heath Jeffery +17 more
wiley +1 more source
Spectral tuning and photoactivation of retinal-binding proteins
Retinal-binding proteins are found in all three domains of life: archaea, eubacteria and eukarya, and are classified into either type 1 or type 2 rhodopsins. These light-transducing proteins share a similar three-dimensional structure consisting of seven
Amora, Tabitha L
core +1 more source
In this study, natural pigments from the hemp (Datisca cannabina L) dye plant were prepared by using KAI(SO4)(2)center dot 12H(2)O (alum), FeSO4 center dot 7H(2)O and SnCl2 center dot 2H(2)O mordants.
ÇAKMAKÇI, EMRAH
core +1 more source
Clinical manifestations of dual‐gene variants in retinitis pigmentosa
Abstract Purpose Retinitis pigmentosa (RP) is an inherited retinal disease (IRD), whereby each affected individual typically harbours pathogenic variants in a single causative gene, yet the disorder exhibits marked genetic heterogeneity, with more than 100 genes reported to underlie RP.
Lasse Wolfram +11 more
wiley +1 more source
Retinal dystrophies simulating geographic atrophy: A diagnostic challenge
Abstract Geographic atrophy (GA) is the chronic loss of retinal pigment epithelium, photoreceptors and choriocapillaris, marking the dry late stage of age‐related macular degeneration (AMD). GA prevalence is expected to rise in the upcoming decades. Advanced GA leads to central scotomas, reducing visual acuity and quality of life, potentially resulting
Johanna M. Colijn +3 more
wiley +1 more source
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič +4 more
wiley +1 more source
Explainable deep learning self‐supervised vision transformer for fundus‐based myopia classification
Abstract Purpose To develop and validate a self‐supervised vision transformer (ViT) for automated three‐class classification of Normal, High Myopia (HM), and Pathologic Myopia (PM) from colour fundus photographs, with anatomically faithful interpretability. Methods A DINOv2 self‐supervised ViT was fine‐tuned using a two‐stage transfer‐learning protocol
Eirini Maliagkani +6 more
wiley +1 more source
Masaaki Saito,1 Tomohiro Iida,1,2 Mariko Kano,1 Kanako Itagaki11Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, 2Department of Ophthalmology, Tokyo Women's Medical University School of Medicine, Tokyo ...
Kano M, Iida T, Saito M, Itagaki K
core

