Results 191 to 200 of about 19,821 (304)

A Dynamic Change of Microglial States Occurs During the Transition From Photoreceptor Degeneration to Regeneration in Zebrafish pde6c Mutants

Glia, Volume 74, Issue 6, June 2026.
Zebrafish pde6c mutants undergo photoreceptor degeneration from 5 dpf, but rods regenerate from 4 wpf. scRNA‐seq of retinal microglia reveals dynamic change of states between 5 dpf and 4 wpf. Two states emerge specifically during regeneration. ABSTRACT Microglia, brain‐resident immune cells, maintain brain homeostasis.
Darshini Ravishankar, Yuki Takeuchi, Ichiro Masai   +2 more
wiley   +1 more source

Natural color biofactories: advancing the spectrum of pigment production in phototrophic microbes. [PDF]

FEMS Microbes
Norena-Caro DA, Posada-Uribe LF, Morales-Ibarria MG, Canto-Encalada G, Álvarez-Láinez ML, Zúñiga C.   +5 more
europepmc   +1 more source

HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma

International Journal of Cancer, Volume 158, Issue 11, Page 2957-2971, 1 June 2026.
What's new? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang, Ken Yamaguchi, Kohei Hamada, Yuko Hosoe, Yuka Mise, Sachiko Kitamura, Zhihong Liu, Hairong Wei, Zhenhai Gao, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Rin Mizuno, Taito Miyamoto, Junzo Hamanishi, Masaki Mandai   +15 more
wiley   +1 more source

Stabilizing effects of geraniol on native and pathogenic M39R rhodopsin variants. [PDF]

Front Neurosci
Fernandez-Gonzalez P, Das J, Cruz A, Perez JJ, Garriga P.   +4 more
europepmc   +1 more source

Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish [PDF]

, 2019
Han, Shanshan, Hu, Xuebin, Huang, Yuwen, Jiang, Tao, Li, Jingzhen, Liu, Fei, Liu, Mugen, Liu, Xiliang, Lv, Yuexia, Qin, Yayun, Qu, Zhen, Reilly, James, Shu, Xinhua, Tang, Zhaohui, Tu, Jiayi, Xie, Shanglun, Yimer, Tinsae Assefa, Yu, Shanshan   +17 more
core   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

British Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

Effect of carotenoids supplementation on visual function in Chinese adults free of retinal disease: protocol for the CSV double-blind, randomised, placebo-controlled trial. [PDF]

BMJ Open
Xu K, Tang X, Zhang Y, Tay JP, Zhang S, Qin Y, Wong W, He M, Han X.   +8 more
europepmc   +1 more source

Investigating the Effect of Diet on Nutrient Concentration in Eggs: How Your Breakfast Might Be Healthier than You Think [PDF]

, 2007
Stewart, Gwen
core   +1 more source

Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease

Immunology, Volume 178, Issue 2, Page 218-230, June 2026.
This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley   +1 more source

Advances in Synthetic Strategies for Microalgal Carotenoid Enhancement and Emerging Applications. [PDF]

Antioxidants (Basel)
Xu P, Wang Y, Luo C, Xue A, Du H, Chen J.   +5 more
europepmc   +1 more source