Results 191 to 200 of about 283,262 (306)

Visual cycle-derived bisretinoids as endogenous natural products: enzyme-free formation, photochemical reactivity, and retinal degeneration.

Nat Prod Rep
Kim HJ, Sparrow JR, Jang YP.
europepmc   +1 more source

RGR-Mediated Photopic Visual Cycle and Oxidative Stress: Potential Mechanisms for Cone Vision Impairment and Retinal Degeneration in Retinitis Pigmentosa Linked to D1080N-IRBP. [PDF]

J Neurosci
Li S, Sato K, Jin M.
europepmc   +1 more source

20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy

Journal of Microscopy, EarlyView.
Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford, Colette J. Mustard, Nicole Brace, Antonia L. Pritchard   +3 more
wiley   +1 more source

Turning Red to Green Repeatedly: Ancestral LWS Duplications Drive Convergent Visual Tuning in Teleost Fishes. [PDF]

Mol Ecol
Cortesi F, Escobar-Camacho D, Sommer GM, Luehrmann M, Hidber F, Deupi X, Carleton K, Musilova Z.   +7 more
europepmc   +1 more source

Tubulointerstitial Nephritis With Uveitis Syndrome: A Case Report and Review of Literature [PDF]

Clin Case Rep
ABSTRACT TINU syndrome should be considered in any child presenting with unexplained renal dysfunction and uveitis. Early recognition and a multidisciplinary approach involving nephrology and ophthalmology are essential to prevent irreversible renal and ocular damage.
Alshaiban A.
europepmc   +2 more sources

A Double‐Blind Randomised Controlled Crossover Trial of the Effect of Blue‐Enriched Ambient Light on Sleep in Older Adults With Sleep Disturbance: The CleverLights Study

Journal of Sleep Research, EarlyView.
ABSTRACT Light interventions have been investigated for treating sleep disturbances in older adults; however, findings are mixed. This proof‐of‐concept trial investigated the effect of blue‐enriched ambient light on electroencephalographic (EEG) sleep in older adults with self‐reported poor sleep.
Teha B. Pun, Craig L. Phillips, Nathaniel S. Marshall, Matthew Rahimi, Rick Wassing, Maria Comas, Angela L. D'Rozario, Camilla M. Hoyos, Delwyn J. Bartlett, Wenye Hu, Sharon L. Naismith, Sean Cain, Svetlana Postnova, Ronald R. Grunstein, Christopher J. Gordon   +14 more
wiley   +1 more source

Human blue cone opsin regeneration involves secondary retinal binding with analog specificity

Human color vision is mediated by the red, green, and blue cone visual pigments. Cone opsins are G-protein-coupled receptors consisting of an opsin apoprotein covalently linked to the 11-cis-retinal chromophore.
Srinivasan, Sundaramoorthy, Ramon Portés, Eva, Morillo Cazorla, Margarita, Fernández Sampedro, Miguel Ángel, Cordomi, Arnau, Garriga Solé, Pere, Jiménez Rosés, Mireia   +6 more
core  

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Complete Regression of bilateral Choroidal Metastases secondary to a Cutaneous Melanoma under Immunotherapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Yenny Angela, Alena Riesmeier, Ralf Gutzmer, Miltiadis Fiorentzis, Nikolaos E. Bechrakis, Carsten Framme, Ekaterina Sokolenko   +6 more
wiley   +1 more source

Oral Lichenoid Lesions in Patients With Dyskeratosis Congenita: A Retrospective Case Series

Oral Diseases, EarlyView.
ABSTRACT Background Dyskeratosis congenita (DKC) is a rare inherited multisystem disorder primarily affecting the mucocutaneous and hematopoietic systems. Classically, it presents with the ectodermal triad of reticulate skin pigmentation, nail dystrophy, and oral leukoplakia.
Yehuda Zadik, Ori Finfter, Tevel Amiel, Amina Massarwa, Refael Cohen, Jawad Abu Tair, Anna Novikov, Polina Stepensky, Irina Zaidman, Ehud Even‐Or   +9 more
wiley   +1 more source