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2006
Retinal pigment epithelium (RPE) arises from neuroectoderm and plays a key role in support of photoreceptor functions. Several degenerative eye diseases, such as macular degeneration or retinitis pigmentosa, are associated with impaired RPE function that may lead to photoreceptor loss and blindness. RPE derived from human embryonic stem (hES) cells can
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Retinal pigment epithelium (RPE) arises from neuroectoderm and plays a key role in support of photoreceptor functions. Several degenerative eye diseases, such as macular degeneration or retinitis pigmentosa, are associated with impaired RPE function that may lead to photoreceptor loss and blindness. RPE derived from human embryonic stem (hES) cells can
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Retinal Pigment Epithelium and Endothelium
Archives of Ophthalmology, 1986To the Editor. —The recent reports on the interactions between retinal pigment epithelium (RPE) and endothelium in vitro point out that an RPElocated inhibitor of neovascularization and an endothelium-located chemoattractant for RPE cells explain only part of the story of how neovascularization and the status quo at Bruch's membrane are controlled.1 ...
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Retinitis Pigmentosa Without Pigment
American Journal of Ophthalmology, 1976Sixty-eight consecutive patients with retinitis pigmentosa were studied to determine the frequency of the nonpigmented form of the disease. There was an overall incidence of 22%. Fifty percent of all cases had no characteristic pigmentation, if the duration of night vision difficulty was three years or less.
J T, Pearlman, T P, Flood, S R, Seiff
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Retinal Pigment Epithelial Hamartoma
Ophthalmology, 1983Retinal pigment epithelial (RPE) hamartomas are uncommon tumefactions characterized by proliferation of RPE and glial cells and blood vessels involving the RPE, retina, and adjacent vitreous. 1-5 Although these lesions have little, if any, growth potential they may appear similar to various malignancies, which has led to unnecessary enucleation of the ...
W D, Reynolds, B G, Goldstein
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Renaissance of the Retinal Pigment Epithelium
Archives of Ophthalmology, 1972THE APPLICATION of recent advances in laboratory methods to the study of individual intraocular structures has greatly enhanced our ability to evaluate their function in health and disease. Nowhere is this more apparent than in the investigation of the retinal pigment epithelium where the utilization of light and electron microscopy coupled with ...
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Acute Retinal Pigment Epitheliitis
American Journal of Ophthalmology, 1995We examined a patient with acute retinal pigment epitheliitis before the development of the characteristic pigmentary retinopathy.Three days after onset of blurred vision in her left eye, a 25-year-old woman had a visual acuity of L.E.: 20/40 -2. There were uniform outer retinal golden-colored vacuoles in the area of subsequent foveal pigmentary ...
J K, Luttrull, M E, Chittum
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The Polarity of the Retinal Pigment Epithelium
Traffic, 2001The diversity of epithelia in the body permits a multitude of organ‐specific functions. One of the foremost examples of this is the retinal pigment epithelium. Located between the photoreceptors of the retina and their principal blood supply, the choriocapillaris, the retinal pigment epithelium is critical for the survival and function of retinal ...
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Acute Retinal Pigment Epitheliitis
American Journal of Ophthalmology, 1997To report a patient with acute retinal pigment epitheliitis examined less than 24 hours after onset of symptoms.One day after the onset of blurred vision in her left eye, a 33-year-old woman had a best-corrected visual acuity of LE, 20/60 -2. The left eye had classic uniform golden-colored nodules in a honeycomb pattern in the foveal retinal pigment ...
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Retinal involvement in pigment dispersion syndrome
International Ophthalmology, 1996Retinal involvement has been documented in a number of patients with pigment dispersion syndrome, which also appears to be associated with a higher than normal risk of retinal detachment. We studied 24 patients with this syndrome to determine the prevalence of lattice degeneration and other retinal disorders associated with a predisposition to ...
Scuderi, G +3 more
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The Retinal Pigment Epithelium
Archives of Ophthalmology, 1967The comparative histology of the retinal pigment epithelium (RPE) of the following species was studied by examining bleached flat preparations and cross sections of the cells: human, monkey, rat, rabbit, sheep, cow, dog, and chicken. The variations noted among the cells of the different species involved cell size, nuclear size, number of nuclei per ...
M O, Ts'o, E, Friedman
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