Adipose‐Derived Mesenchymal Stem Cells: Isolation, Origin, Phenotype Applications, and Challenges
MedComm, Volume 7, Issue 11, November 2026.Bridging basic biology to clinical translation, this review systematically explores the in vivo origins and evolving isolation techniques of AD‐MSCs. We dissect their diverse phenotype applications orchestrated by immunometabolic reprogramming, mitochondrial transfer, and extracellular vesicles.
Ziyang Liu +7 more
wiley +1 more source
Targeted Protein Degradation: From Molecular Mechanisms to Emerging Therapeutic Strategies
MedComm, Volume 7, Issue 11, November 2026.Graphical overview of targeted protein degradation: mechanisms, molecular determinants, delivery strategies, and therapeutic development. This graphical abstract summarizes the major degradation pathways involved in targeted protein degradation, including the ubiquitin–proteasome system, endocytosis–lysosome pathway, and autophagy‐dependent degradation.
Huaijuan Guo +8 more
wiley +1 more source
Müller glial cells for regeneration, retinal organoids, cell transplantation, and neuroprotection
María Miranda +4 more
openalex +1 more source
Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.A young dog presented with progressive unilateral hindlimb lameness and marked erythrocytosis. Diagnostic investigations excluded secondary causes and confirmed primary erythrocytosis. Targeted vascular ultrasonography identified a right external iliac venous thrombus as the suspected cause of lameness.
Robyn Belch +8 more
wiley +1 more source
In Vivo Partial Cell Reprogramming With Yamanaka Factors Reduced Ischemic Brain Damage in Aging Mice
Aging Cell, Volume 25, Issue 11, November 2026.Short‐term cyclic partial reprogramming with Yamanaka factors protects aged mice from ischemic brain injury, preserving cognitive function, myelin integrity, and neuronal density, supporting partial reprogramming as a promising neuroprotective intervention in aging.
Paula R. Mallavibarrena +5 more
wiley +1 more source
Mitochondria transplantation preserves retinal ganglion cells and promotes CNS axonal regeneration
Ajay Ashok +10 more
openalex +1 more source
TOP2A Maintains Heterochromatin Stability by Sustaining LMNB1 Expression to Counteract Senescence
Aging Cell, Volume 25, Issue 11, November 2026.Depletion of TOP2A accelerates MSC senescence and disrupts heterochromatin integrity. TOP2A directly regulates LMNB1 expression to maintain MSC nuclear integrity and epigenomic stability. Overexpression of TOP2A counteracts MSC senescence through Lamin B1‐mediated chromatin reorganization and epigenomic stabilization.
Ke Cheng +15 more
wiley +1 more source
Chemokine-guided Stem Cell Migration for Retinal Regeneration: A Systematic Review [PDF]
Ashish Chander +3 more
openalex +1 more source
Determinant Factors of Self‐Care Deficit in People With Chronic Wounds: A Scoping Review
Journal of Advanced Nursing, Volume 82, Issue 11, Page 9609-9625, November 2026.ABSTRACT Aims To identify and synthesise the scientific evidence on determinants of self‐care deficits in people with chronic wounds. Design Scoping review based on the Joanna Briggs Institute guidelines. Methods This scoping review was conducted by a review team responsible for study screening, data extraction and synthesis.
Janislei Soares Dantas +4 more
wiley +1 more source