Artificial Intelligence-Assisted Analysis of Retinal Pigment Epithelium Tears in Patients with Neovascular Age-Related Macular Degeneration Treated with Aflibercept (2 mg and 8 mg) and Faricimab: A Single-Centre Retrospective Case Series. [PDF]
Eggarter V +7 more
europepmc +1 more source
Bone marrow mesenchymal stem cells (BMSCs) promote tendon injury repair by enhancing tenocyte function and regulating the FTO/m6A/ELOB axis. Mechanistically, BMSCs lead to the upregulation of FTO and m6A modification, which subsequently suppresses ELOB expression.
Zhao‐Rong Dai +2 more
wiley +1 more source
Dynamic Tear Film Stability Assessed via an Open-View Double-Pass Imaging System. [PDF]
Tsoukalas S +6 more
europepmc +1 more source
Using micro computed tomography, light microscopy and transmission electron microscopy, this study reveals that the conjunctival portions of the corneal epithelial and spectacular endothelial lining in the eye of the short‐nosed sea snake Aipysurus apraefrontalis possess high densities of microvilli to increase the surface area and two types of ...
H. Barry Collin +4 more
wiley +1 more source
Fenofibrate in ophthalmology: therapeutic efficacy and mechanisms. [PDF]
Ho SC +6 more
europepmc +1 more source
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li +4 more
wiley +1 more source
Stage-associated immunoproteomic profiling of serum autoantibody-captured retinal antigens in age-related macular degeneration. [PDF]
Lin H +6 more
europepmc +1 more source
Advances in FGF/FGFR Signaling: Implications for Disease and Therapy
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song +4 more
wiley +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Primary Laser Photocoagulation for Giant Retinal Tears Without Retinal Detachment: Two Case Reports and Review of the Literature. [PDF]
Orfi S +3 more
europepmc +1 more source

