Results 211 to 220 of about 261,050 (242)

Migraine: Epidemiology, Risk Factors, Pathophysiology, and Treatment

MedComm, Volume 7, Issue 9, September 2026.
Migraine is a highly prevalent, female‐predominant, and disabling brain disorder shaped by genetic susceptibility, hormonal influences, modifiable attack factors, and comorbidity‐related progression. This review integrates current evidence on migraine epidemiology, phase‐specific neurovascular and neuroglial mechanisms, including CGRP signaling and ...
Weiwei Lu, Yuan Zhang, Chen Shi, Yu Tao, Shaoxin Li, Yufang Sun, Fuhai Ji, Dongsheng Jiang, Terrance P. Snutch, Jin Tao   +9 more
wiley   +1 more source

High‐Content CRISPR Screening: Methods and Applications

MedComm, Volume 7, Issue 9, September 2026.
High‐content CRISPR screening represents a paradigm shift in functional genomics, moving beyond traditional survival‐based readouts to enable multidimensional mapping of genotype–phenotype relationships. This review systematically outlines the methodological evolution of this approach, detailing advances in perturbation modalities, delivery systems ...
Yike Zhang, Yimeng Zhang, Xudong Tang, Xinyu Deng, Yitian Zhou, Yanfeng Wu, Jianhua Luo   +6 more
wiley   +1 more source

Graded traumatic brain injury severity differentially modulates microglial and astrocytic polarization states and response to minocycline

Neuroprotection, Volume 4, Issue 3, Page 275-294, September 2026.
Schematic diagram of the experimental design and key findings of traumatic brain injury (TBI) with varying severities. Mild, moderate, and severe TBI were induced in the right motor cortex of mice using the controlled cortical impact (CCI) method, with impact depths of 0.5, 1.0, and 2.0 mm, respectively. A subset of severe TBI mice received minocycline
Yan Yu, Chen Wang, Jinyu Zhu, Jiahui Du, Hao Li, Shuyi Ning, Rui Yang, Yiwen Ma, Mengyuan Yuan, Wei Shen, Huailin Wang, Huihui Jiang, Liping Chen, Haitao Wu   +13 more
wiley   +1 more source

Accuracy of Retinal Pigment Epithelium (RPE) undulations (Oscillatory sign) as an optical coherence tomography biomarker of acute RPE tears. [PDF]

Int J Retina Vitreous
Shettigar MP, Chhablani J, Tyagi M, Narula R, Narayanan R.   +4 more
europepmc   +1 more source

A Review of the Therapeutic Potential of Stem Cell‐Derived Nanocarriers to Treat Neurological Disorders

ChemistryOpen, Volume 15, Issue 9, September 2026.
Neurological disorders (NDs) are characterized by substantial loss of specific neurons, with Alzheimer's and Parkinson's diseases being the most frequent NDs and nearly 99% of all “foreign substances” are prohibited from entering the brain by the blood‐brain barrier (BBB) and the blood‐cerebrospinal fluid barrier (CFB).
Nnamdi Ikemefuna Okafor, Ahmed Abdelgader, Magdi Abobaker, Yahya E. Choonara   +3 more
wiley   +1 more source

A Qualitative Exploration of the Decision Not to Take Part in Colorectal Cancer Screening Among Women Living in Lower Socio‐Economic Areas

Psycho-Oncology, Volume 35, Issue 9, September 2026.
ABSTRACT Background Organized colorectal (CRC) screening programmes offer an opportunity to reduce the burden of the disease on populations. CRC screening participation among women is substantially lower than breast or cervical cancer screening. Uptake is also lower in areas of greater deprivation which could exacerbate inequalities in CRC; however ...
Nicholas Clarke, Lucy Hayden, Alan Smith, Linda Sharp, Christian von Wagner, Therese Mooney, Pamela Gallagher   +6 more
wiley   +1 more source

Obesity and Eye Diseases. [PDF]

Nutrients
Pieńczykowska K, Bryl A, Mrugacz M.
europepmc   +1 more source

Artificial intelligence‐enabled cytopathological interpretation of fluorescence microscopy images via a multimodal large language model

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Quantitative analysis of fluorescence microscopy images remains a significant challenge in cytopathological assessments, as subjective interpretation and inter‐observer variability hinder reproducibility and standardization of classifications. In this study, an artificial intelligence‐assisted analytical framework utilizing a multimodal large ...
Atakan Tevlek, Ozgecan Ocakcı, Beyza Emeksiz   +2 more
wiley   +1 more source

Short-term adjunctive use of a liposomal tear substitute after repeated intravitreal therapy: a randomized pilot study. [PDF]

Int Ophthalmol
Cagini C, Messina M, Fiore T, Chiruzzi ML, Frenguelli M, Crescenzi L, Poddi M.   +6 more
europepmc   +1 more source

Advanced Electrospun Nanofiber Epidermal Electronics for Electrophysiological Monitoring: From Conformal Interfaces to Multimodal Closed‐Loop Systems

Rare Metals, Volume 45, Issue 9, September 2026.
ABSTRACT Epidermal bioelectronics is a transformative technology for continuous health monitoring and human‐computer interaction. However, the mechanical and physiological mismatch at the skin–device interface limits its long‐term application. Electrospun nanofiber membranes (ENMs), with their unique three‐dimensional hierarchical porous network and ...
Jiahua Ni, Jing Lu, Nianzhe Wu, Jiahui Tang, Tiantian Chen, Xiaonong Zhang, Wenhui Wang, Zhe Zhao   +7 more
wiley   +1 more source