Cholesterol Deficiency Directs Autophagy‐Dependent Secretion of Extracellular Vesicles
Journal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.Inhibition of cholesterol biosynthesis within models of rare disease and cancer causes increased release of small extracellular vesicles (sEVs) with distinct biological properties. Mechanistically, cholesterol depletion leads to impaired autophagic flux, redirection of autophagosomes to late endosomes, and subsequently increased sEV secretion ...
Jazmine D. W. Yaeger +6 more
wiley +1 more source
Branch Retinal Vein Occlusion followed by Central Retinal Vein Occlusion
Journal of Ophthalmic & Vision Research, 2009 Siamak Moradian, Ramin Nourinia
doaj
Comment on: "Risk factors and incidence of macular edema in eyes with retinal vein occlusion after uneventful cataract surgery: The MEVO study". [PDF]
Indian J OphthalmolZhang X, Chen J.
europepmc +1 more source
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Central Retinal Vein Occlusion Associated With Progestin-Only Contraceptive Implant Use. [PDF]
Case Rep Ophthalmol MedChu JPO, Sia DIT.
europepmc +1 more source
MedComm, Volume 7, Issue 1, January 2026.The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li +5 more
wiley +1 more source
Associations between obstructive sleep apnoea and the development and severity of retinal vein occlusion. [PDF]
Eye (Lond)Jeong H +4 more
europepmc +1 more source
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, Volume 46, Issue 1, Page 272-298, January 2026.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Neurology and Clinical Neuroscience, Volume 14, Issue 1, Page 46-53, January 2026.ABSTRACT Background Idiopathic intracranial hypertension is a syndrome characterized by symptoms and signs of raised intracranial pressure without a secondary cause. It primarily affects young obese women who present with headache and papilledema. We report the clinical presentation, brain imaging findings and outcomes of patients with IIH from two ...
Bandlakazi Sukwana‐Ncemane +2 more
wiley +1 more source
Aqueous humor cytokine levels in retinal vein occlusion patients with suboptimal response to anti-VEGF therapy and the correlation with OCT imaging biomarkers. [PDF]
Eur J Med ResGong Y +7 more
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