Results 131 to 140 of about 137,312 (290)

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Generative Adversarial Network Combined with SE-ResNet and Dilated Inception Block for Segmenting Retinal Vessels. [PDF]

Comput Intell Neurosci, 2022
Yue C, Ye M, Wang P, Huang D, Lu X.
europepmc   +1 more source

Hypertensive retinopathy in pre‐eclampsia and its association with disease severity and neonatal outcomes: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone, Francesco Matarazzo, Mariarosaria Motta, Marika Rovetto, Michele Rinaldi, Maurizio Guida, Ciro Costagliola   +6 more
wiley   +1 more source

A Fundus Image Dataset for AI-based Artery-Vein Vessel Segmentation

Scientific Data
Retinal artery-vein vessels are associated with systemic chronic diseases and cardiovascular diseases. Therefore, the accurate quantitative analysis of retinal artery-vein vessels is the preliminary basis of clinical diagnosis.
Zhuo Deng, Weihao Gao, Zheng Gong, Run Gan, Lu Chen, Shaochong Zhang, Lan Ma   +6 more
doaj   +1 more source

Evaluation of Morphological Changes in Retinal Vessels in Type 1 Diabetes Mellitus Patients with the Use of Adaptive Optics. [PDF]

Biomedicines, 2022
Matuszewski W, Gontarz-Nowak K, Harazny JM, Bandurska-Stankiewicz E.   +3 more
europepmc   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Vessel Segmentation in Retinal Images Using Multi-scale Line Operator and K-Means Clustering

Journal of Medical Signals and Sensors, 2014
Detecting blood vessels is a vital task in retinal image analysis. The task is more challenging with the presence of bright and dark lesions in retinal images. Here, a method is proposed to detect vessels in both normal and abnormal retinal fundus images
Vahid Mohammadi Saffarzadeh, Alireza Osareh, Bita Shadgar   +2 more
doaj  

Morphological characteristics of retinal vessels in eyes with high myopia: Ultra-wide field images analyzed by artificial intelligence using a transfer learning system. [PDF]

Front Med (Lausanne), 2022
Mao J, Deng X, Ye Y, Liu H, Fang Y, Zhang Z, Chen N, Sun M, Shen L.   +8 more
europepmc   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Evaluation of Macular Retinal Vessels and Histological Changes in Two Cases of COVID-19. [PDF]

Biomedicines, 2021
Hernandez M, González-Zamora J, Recalde S, Moreno-Orduña M, Bilbao-Malavé V, Saenz de Viteri M, Landecho MF, Fernandez-Robredo P, García-Layana A.   +8 more
europepmc   +1 more source