Results 181 to 190 of about 145,462 (345)

Cancer and Accelerated Aging Research at the National Institutes of Health, 2013–2023: A Grant Portfolio Analysis

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background The purpose of this study was to describe the characteristics of the NIH‐funded grant portfolio focused on cancer and accelerated aging. Methods Research project grants focused on cancer survivors and aging trajectories that were newly funded during fiscal years 2013 through 2023 were identified by first using a text mining ...
Lisa Gallicchio   +5 more
wiley   +1 more source

The expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers. [PDF]

open access: yes, 2015
BackgroundStudies of familial cancers have found that only a small subset of tissues are affected by inherited mutations in a given tumour suppressor gene (TSG) or proto-oncogene (POG), even though the mutation is present in all tissues.
Muir, Brian, Nunney, Leonard
core  

Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer

open access: yesJournal of Internal Medicine, EarlyView.
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic   +3 more
wiley   +1 more source

GD2-specific CAR T cells encapsulated in an injectable hydrogel control retinoblastoma and preserve vision

open access: yesNature Cancer, 2020
Kai Wang   +7 more
semanticscholar   +1 more source

Expression patterns of melanin‐related genes are linked to crypsis and conspicuousness in a pumpkin toadlet

open access: yesMolecular Ecology, EarlyView.
Abstract Colour signals play pivotal roles in different communication systems, and the evolution of these characters has been associated with behavioural ecology, integumentary production processes and perceptual mechanisms of the species involved. Here, we present the first insight into the molecular and histological basis of skin colour polymorphism ...
Juliane P. C. Monteiro   +7 more
wiley   +1 more source

Computational modeling of plant root development: the art and the science

open access: yesNew Phytologist, EarlyView.
Summary Plant root development, like any developmental process, arises from the interplay between processes like gene expression, cell–cell signaling, cell growth and division, and tissue mechanics, which unfold over a wide range of temporal and spatial scales.
Kirsten H. ten Tusscher
wiley   +1 more source

THE GENETICS OF RETINOBLASTOMA

open access: bronze, 1944
A D Griffith, Arnold Sorsby
openalex   +1 more source

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