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Bilateral retinoblastoma with ectopic intracranial retinoblastoma: Trilateral retinoblastoma
Cancer Genetics and Cytogenetics, 1982In 11 patients, bilateral retinoblastoma presented at a mean age of 6 months and pineoblastoma at 4 years. We suggest that the hereditary multicentric retinoblastoma arose in vestigeal photoreceptors in the pineal as well as in the hypothetical retinoblasts of the retina.
J L, Bader +6 more
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2004
Retinoblastoma (Rb) is a malignant tumor that originates from developing retina. Diagnosis based on clinical signs and symptoms and is usually made in children under the age of five years. Mutations in both alleles of the RB1 gene are a prerequisite for this tumor to develop.
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Retinoblastoma (Rb) is a malignant tumor that originates from developing retina. Diagnosis based on clinical signs and symptoms and is usually made in children under the age of five years. Mutations in both alleles of the RB1 gene are a prerequisite for this tumor to develop.
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Trilateral retinoblastoma: ocular and pineal retinoblastomas
Journal of Neurosurgery, 1985✓ Trilateral retinoblastomas, the syndrome of bilateral retinoblastoma associated with ectopic retinoblastoma in the pineal gland, is rare but well recognized. In contrast to bilateral retinoblastomas alone, the ocular retinoblastomas in trilateral retinoblastoma develop before the age of 6 months, and a family history positive for retinoblastoma is ...
D L, Johnson +4 more
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Pediatric Blood & Cancer, 2007
AbstractBackgroundTrilateral retinoblastoma (TRB) is a syndrome consisting of unilateral or bilateral hereditary retinoblastoma (Rb) associated with an intracranial neuroblastic tumor. Although its incidence is low, the prognosis is very poor. This article reports four cases of TRB and discusses the role of neuroimaging screening for early detection ...
Célia B G, Antoneli +5 more
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AbstractBackgroundTrilateral retinoblastoma (TRB) is a syndrome consisting of unilateral or bilateral hereditary retinoblastoma (Rb) associated with an intracranial neuroblastic tumor. Although its incidence is low, the prognosis is very poor. This article reports four cases of TRB and discusses the role of neuroimaging screening for early detection ...
Célia B G, Antoneli +5 more
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American Journal of Ophthalmology, 1975
A grossly cystic retinoblastoma, presumably a form of the diffuse infiltrating type, mimicked uveitis in an 81/2-year-old boy. A review of 44 cases indicated that grossly (clinically) detectably cysts are rare in this neoplasm, although microcysts are relatively common.
J, Ginsberg, A G, Spaulding, T, Asbury
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A grossly cystic retinoblastoma, presumably a form of the diffuse infiltrating type, mimicked uveitis in an 81/2-year-old boy. A review of 44 cases indicated that grossly (clinically) detectably cysts are rare in this neoplasm, although microcysts are relatively common.
J, Ginsberg, A G, Spaulding, T, Asbury
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Archives of Ophthalmology, 1995
To apply modern techniques of molecular cell biology and to revisit the old question of the cell of origin for retinoblastoma in hopes of gaining a better understanding of the retinoblastoma gene's antioncogenic mechanisms.Twenty-two consecutively accessed retinoblastomas were examined with immunocytochemical techniques for numerous retinal proteins ...
T M, Nork +3 more
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To apply modern techniques of molecular cell biology and to revisit the old question of the cell of origin for retinoblastoma in hopes of gaining a better understanding of the retinoblastoma gene's antioncogenic mechanisms.Twenty-two consecutively accessed retinoblastomas were examined with immunocytochemical techniques for numerous retinal proteins ...
T M, Nork +3 more
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Journal of Pediatric Ophthalmology & Strabismus, 2003
Carol L, Shields +2 more
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Carol L, Shields +2 more
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Retinoblastoma [Il retinoblastoma]
2013Retinoblastoma is the most frequently diagnosed intraocular malignancy in infants. Recently, there have been significant advances in the management of this disease. New therapeutic strategies, such as superselective intra-arterial chemotherapy and periocular/intravitreal chemotherapy, have been added to conservative treatments with a long consolidated ...
D'Ambrosio, Alfonso +10 more
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