Results 101 to 110 of about 97,585 (218)

The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes [PDF]

, 2014
Copyright © 2014. Published by Elsevier Inc. Acknowledgments This work was supported by the British Heart Foundation Intermediate Basic Research Fellowship FS/09/026/27398 to N.M.
McIlroy, George David, Mody, Nimesh
core   +1 more source

Release of retinol and denaturation of its plasma carrier, retinol-binding protein

Folding and Design, 1998
Retinol is tightly packed inside the structure of its plasma carrier (retinol-binding protein, RBP). It was found that retinol release from RBP to aqueous solutions is facilitated by either very low pH or very high temperatures (i.e. by non-physiological conditions that cause protein denaturation).
Bychkova, Valentina E., Dujsekina, Alexandra E., Fantuzzi, Andrea, Ptitsyn, Oleg B., Rossi, Gian-Luigi   +4 more
openaire   +2 more sources

Crystal structure of liganded and unliganded forms of bovine plasma retinol-binding protein

Journal of Biological Chemistry, 1993
The three-dimensional structures of bovine plasma retinol-binding protein (bRBP) complexed with retinol (space group P2(1)2(1)2(1), a = 46.08, b = 49.12, c = 76.10 A) and of the unliganded protein prepared in vitro by extracting retinol with ethyl ether (space group P2(1)2(1)2(1), a = 46.55, b = 48.97, c = 76.87 A) have been solved at 1.9 and 1.7 A ...
ZANOTTI, GIUSEPPE, BERNI R., MONACO H. L.   +2 more
openaire   +4 more sources

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview [PDF]

, 2017
The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available ...
Abbracchio, MP, Al-Hosaini, K, Aldrich, R, Alexander, SPH, Arumugam, TV, Attali, B, Barnes, NM, Bathgate, R, Beart, PM, Becirovic, E, Bettler, B, Biel, M, Birdsall, NJ, Blaho, V, Boison, D, Bryant, C, Bräuner-osborne, H, Bröer, S, Buneman, OP, Burnstock, G, Bäck, M, Calo, G, Catterall, WA, Ceruti, S, Chan, SL, Chandy, KG, Chazot, P, Chiang, N, Christopoulos, A, Chun, JJ, Chung, JJ, Cidlowski, JA, Clapham, DE, Clapp, L, Connor, MA, Cox, HM, Davenport, AP, Davies, JA, Davies, P, Dawson, PA, Decaen, P, Dent, G, Doherty, P, Douglas, SD, Dubocovich, ML, Fabbro, D, Faccenda, E, Fong, TM, Fowler, CJ, Frantz, A, Fuller, P, Fumagalli, M, Futerman, AH, Gainetdinov, RR, Gershengorn, MA, Goldin, A, Goldstein, SAN, Goudet, C, Gregory, K, Grissmer, S, Gundlach, AL, Hagenbuch, B, Hamann, J, Hammond, JR, Hancox, JC, Hanson, J, Hanukoglu, I, Harding, SD, Hay, DL, Hobbs, AJ, Hollenberg, AN, Holliday, ND, Hoyer, D, Ijzerman, AP, Inui, KI, Irving, AJ, Ishii, S, Jacobson, KA, Jan, LY, Jarvis, MF, Jensen, R, Jockers, R, Kaczmarek, LK, Kanai, Y, Karnik, S, Kellenberger, S, Kelly, E, Kemp, S, Kennedy, C, Kerr, ID, Kihara, Y, Kukkonen, J, Larhammar, D, Marrion, NV, Pawson, AJ, Peters, JA, Sharman, JL, Southan, C, Spedding, M, Striessnig, J   +99 more
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Evaluation of drug-induced hepatotoxicity by plasma retinol binding protein.

In vivo (Athens, Greece), 2002
Retinol binding protein (RBP) in the plasma of rats treated with D-galactosamine was monitored to establish whether its level can be used to evaluate drug-induced hepatotoxicity. Blood was withdrawn by heart puncture at 0 hours and 12 hours after the administration of D-galactosamine (400 mg/kg body weight i.p.) to rats. Lactate dehydrogenase (LDH) and
Masanao, Isozaki, Yasuhiro, Masubuchi, Toshiharu, Horie   +2 more
openaire   +1 more source

Carboxy‐terminal sequence of retinol‐binding protein from human plasma

FEBS Letters, 1972
White, G.H., Weston, S.M., Glover, J.
openaire   +2 more sources

Characterization of bovine plasma retinol-binding protein and evidence for lack of binding between it and other bovine plasma proteins.

Journal of Biological Chemistry, 1975
J. Heller
semanticscholar   +1 more source

Early onset preeclampsia is characterized by altered placental lipid metabolism and a premature increase in circulating FABP4 [PDF]

, 2010
Preeclampsia is a pregnancy-associated disorder that manifests as a sudden increase in maternal blood pressure accompanied by proteinuria. Because the placenta is a key organ in preeclampsia, we used proteomic and lipidomic analyses to compare placentae ...
Aaron Booy, Delfina Siroen, Gilles Lajoie, Jennifer Ballard, Nicholas Carruthers, Victor H. Han   +5 more
core   +1 more source

Structural studies on bovine plasma retinol binding protein (RBP) [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 1993
G. Zanotti, R. Berni, P. Spadon, H. L. Monaco   +3 more
openaire   +1 more source

Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease [PDF]

, 2015
Transthyretin amyloidosis is a conformational pathology characterized by the extracellular formation of amyloid deposits and the progressive impairment of the peripheral nervous system.
Barroso, E, Coelho, A, Cordeiro, C, Costa, G, Ferreira, A, Gilberto, S, Gomes, R, Mateus, E, Ponces Freire, A, Ribeiro, R, Ribeiro-Silva, C   +10 more
core