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Plasma retinol-binding protein is unlikely to be a useful marker of insulin resistance

Diabetes Research and Clinical Practice, 2008
To assess whether plasma retinol-binding protein (RBP) is a marker of insulin resistance we measured RBP, insulin and glucose in 285 fasting subjects attending a Lipid Disorders Clinic as outpatients. They were grouped as either subjects without diabetes mellitus and with varying degrees of insulin resistance or subjects with diabetes mellitus ...
John G, Lewis   +3 more
openaire   +2 more sources

Circular dichroic studies of human plasma retinol-binding protein and prealbumin

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1972
Abstract Circular dichroic (CD) spectra were obtained on solutions of human plasma retinol-binding protein and prealbumin, the two proteins involved in the transport of vitamin A in plasma. CD spectral studies were also carried out on the following solutions: (1) apo-retinol-binding protein (retinol-binding protein not containing bound retinol); (2 ...
A M, Gotto, S E, Lux, D S, Goodman
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Plasma Retinol-Binding Protein: Structure and Interactions with Retinol, Retinoids, and Transthyretin

2004
Retinol-binding protein (RBP) is the retinol-specific transport protein present in plasma. The available crystal structures of different forms of RBP have provided details of the interactions of this binding protein with retinol, retinoids, and transthyretin (TTR, one of the plasma carriers of thyroid hormones).
ZANOTTI, GIUSEPPE, BERNI R.
openaire   +3 more sources

A new method for purification of human plasma retinol‐binding protein and transthyretin

Biotechnology and Applied Biochemistry, 2003
Retinol is transported in the blood bound to a specific carrier protein called retinol‐binding protein (RBP), which in turn binds to another protein, transthyretin (TTR), a homotetrameric, thyroid‐hormone‐transporting protein. Binding of TTR increases the apparent molecular mass of RBP and thereby prevents glomerular filtration of RBP.
Pullakhandam, Raghu   +2 more
openaire   +2 more sources

Plasma membrane receptor for beta‐lactoglobulin and retinol‐binding protein in murine hybridomas

BioFactors, 1998
AbstractThe aim of the present work was to study the binding of [125I]‐BLGA (β‐lactoglobulin variant A) to the plasma membrane fraction of hybrid cells. This binding increased as a function of time with on‐rate and off‐rate constant at 4.47 ± 0.18× 106 M−1 min−1 and 0.17 ± 0.07 min−1, respectively (n = 3).
Mansouri A   +5 more
openaire   +2 more sources

Crystallization and preliminary X-ray data of human plasma retinol-binding protein

Journal of Molecular Biology, 1983
Crystals of human plasma retinol-binding protein have been obtained from 4.5 M-NaCl buffered at pH 6.8 with 20 mM-cacodylate. The crystals are trigonal with space group R3 and unit cell dimensions, referred to the hexagonal system, a = b = 104.2 A and c = 74.5 A. The crystals diffract to a resolution of 2.0 A.
OTTONELLO, Simone   +5 more
openaire   +3 more sources

Plasma vitamin A and retinol-binding protein in premature and term neonates

The Journal of Pediatrics, 1981
J P, Shenai   +3 more
openaire   +2 more sources

Microalbuminuria is a major determinant of elevated plasma retinol-binding protein 4 in type 2 diabetic patients

Kidney International, 2007
Florian J. Schweigert   +2 more
exaly  

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