Results 101 to 110 of about 1,339,271 (291)

Investigating transthyretin variants H88R and I107V in amyloid priming: From destabilization to complete dissociation

open access: yesThe FEBS Journal, EarlyView.
Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy   +7 more
wiley   +1 more source

Retinol and retinol binding protein 4 levels and COVID-19: a Mendelian randomization study

open access: yesBMC Pulmonary Medicine
Background The Corona Virus Disease 2019 (COVID-19) pandemic has struck globally. Whether the related proteins of retinoic acid (RA) signaling pathway are causally associated with the risk of COVID-19 remains unestablished.
Haixia Wang   +5 more
doaj   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Structural and dynamical studies on human epidermal-type fatty acid binding protein using high-resolution NMR spectroscopy

open access: yes, 2003
Human epidermal-type fatty acid binding protein (E-FABP) belongs to a family of intracellular non-enzymatic 14-15 kDa lipid binding proteins (LBP) that specifically bind and facilitate the transport of fatty acids, bile acids or retinoids.
Gutiérrez González, Luis Horacio
core  

Characterization of post-transcriptional regulatory network of RNA-binding proteins using computational predictions and deep sequencing data [PDF]

open access: yes, 2013
This report is divided into three parts: Data Analysis, Mathematical Modeling and Conclusion and future directions. In the Data Analysis part, various methods and tools for characterizing the post-transcriptional regulatory networks of RNA-binding ...
Mohsen, Khorshid
core   +1 more source

Cellular retinol- and retinoic acid-binding proteins of bovine retina. Purification and properties.

open access: yesJournal of Biological Chemistry, 1978
A three-step purification has been developed for the cellular retinoland cellular retinoic acid-binding proteins from extracts of bovine retina. The two binding proteins elute together in Step 1 (gel filtration) and separate in Step 2 (DEAE-cellulose ...
J. C. Saari, S. Futterman, L. Bredberg
semanticscholar   +1 more source

Physicochemical Quality and Chemical Safety of Commercial Wet Cat Food: Composition, Oxidation, Biogenic Amines, and Trace Elements

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT This study investigated the physicochemical characteristics and chemical safety of commercial wet cat foods marketed in Brazil. Twenty products labeled as beef, chicken and fish flavors were analyzed for proximate composition, pH, lipid and protein oxidation, biogenic amines, and essential and potentially toxic trace elements.
Marina Teixeira de Vries Mársico   +6 more
wiley   +1 more source

Common epitopes of serum retinol-binding proteins: a study with monoclonal antibodies

open access: yes, 1990
Monoclonal antibodies were raised against purified chicken retinol-binding protein. These were characterised extensively with respect to their ability to recognize retinol-binding proteins from different species.
Reddy, K, Adiga, PR, Karande, AA
core  

Identification of essential and non-essential single-stranded DNA-binding proteins in a model archaeal organism

open access: yes, 2011
This work is supported by the The Scottish Universities Life Sciences Alliance (SULSA)Single-stranded DNA-binding proteins (SSBs) play vital roles in all aspects of DNA metabolism in all three domains of life and are characterized by the presence of one ...
Skowyra, Agnieszka   +3 more
core   +1 more source

C-terminal binding proteins: Emerging roles in cell survival and tumorigenesis [PDF]

open access: yes, 2006
Within a cell, the levels and activity of multiple pro- and anti-apoptotic molecules act in concert to regulate commitment to apoptosis. Whilst the balance between survival and death can be tipped by the effects of single molecules, cellular apoptosis ...
Blaydes, J.P.   +3 more
core   +1 more source

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