Results 71 to 80 of about 2,828,478 (157)

Retinol-Binding Protein Interferes with Transthyretin-Mediated β‑Amyloid Aggregation Inhibition

, 2018
β-Amyloid (Aβ) aggregation is causally linked to Alzheimer’s disease. On the basis of in vitro and transgenic animal studies, transthyretin (TTR) is hypothesized to provide neuroprotection against Aβ toxicity by binding to Aβ and inhibiting its ...
Regina M. Murphy, Regina M. Murphy (1553098), Parth Mangrolia, Parth Mangrolia (5578865)   +3 more
core   +1 more source

Structure and tissue distribution of some retinoid-binding proteins [PDF]

, 1983
Vitamin A has, apart from its function in the visual pigments, general effects on several organs. Early signs of vitamin A deficiency include keratinization of epithelia and hyperkeratosis of the skin.
Peterson, P. A., Eriksson, U., Nilsson, M., Jönsson, K. H., Liljas, A., Rask, L., Newcomer, M., Sundelin, J., Das, S., Ronne, H., Norlinder, H., Das, K., Busch, C., Kämpe, O., Laurent, B.   +14 more
core   +1 more source

Vitamin A, cancer treatment and prevention: The new role of cellular retinol binding proteins [PDF]

, 2015
Retinol and vitamin A derivatives influence cell differentiation, proliferation, and apoptosis and play an important physiologic role in a wide range of biological processes. Retinol is obtained from foods of animal origin.
Passeri, D, COSTANZA, GAETANA, Doldo, E, DOLDO, ELENA, Agostinelli, S, Ferlosio, A, FERLOSIO, AMEDEO, ORLANDI, AUGUSTO, ARCURI, GAETANO, Tarquini, C, Arcuri, G, SCIOLI, MARIA GIOVANNA, Orlandi, A, Costanza, G, Scioli, Mg   +14 more
core   +1 more source

Sex-specific associations of serum retinol-binding protein 4 with type 2 inflammatory biomarkers and pulmonary function in adults with asthma

The Egyptian Journal of Bronchology
Background Retinol-binding protein 4 (RBP4) has been linked to immune regulation, but whether its associations with type 2 inflammatory biomarkers (eosinophils and immunoglobulin E (IgE)) and pulmonary function differ by sex in asthma remains unknown ...
Rasha AL-Darraji, Zahraa Abdulaali Al-Mudhafar   +1 more
doaj   +1 more source

The Ov20 protein of the parasitic nematode Onchocerca volvulus - A structurally novel class of small helix-rich retinol-binding proteins

, 1997
Ov20 is a major antigen of the parasitic nematode Onchocerca volvulus, the causative agent of river blindness in humans, and the protein is secreted into the tissue occupied by the parasite.
Price, Nicholas C., Cooper, Alan, Bradley, Jannette E., Goodrick, Lucy E., Kennedy, Malcolm W., Brass, Andrew, Garside, Lisa H., McDermott, Lindsay, Kelly, Sharon M.   +8 more
core   +1 more source

Characteristics of retinol accumulation from serum retinol-binding protein by cultured Sertoli cells [PDF]

, 1989
The uptake of retinol was examined in cultured Sertoli cells when retinol was provided as a complex with the transport protein retinol-binding protein (RBP). Sertoli cells accumulated [3H]retinol in a time- and temperature-dependent manner. At 32 °C, the
Shingleton, Janet L, Ong, David E, Skinner, Michael K   +2 more
core   +1 more source

The Beneficial Role of Retinoids in Glomerular Disease

Frontiers in Medicine, 2015
The primary etiology of CKD is a direct consequence of initial dysfunction and injury of the glomerulus, the main filtration system. Podocytes are terminally differentiated epithelial cells in the glomerulus, whose major function is the maintenance of ...
Sandeep eMallipattu, John Cijiang He
doaj   +1 more source

The retinol-binding cavity in RBP and CRBP.

, 2012
Ligand binding sites show as cartoon and transparent surface respectively. The binding site surface is illustrated by meshed colors according to the electrostatic potential. We show the binding cavity in different directions to facilitate the observation
Yu-Ru Zhang (166483), Jing-Fei Huang (166496), Yu-Qi Zhao (166490)   +2 more
core   +1 more source

ABO blood group-dependent association of serum retinol-binding protein 4 with eosinophilic inflammation and spirometric parameters in adults with asthma

Monaldi Archives for Chest Disease
Growing evidence links retinol binding protein-4 (RBP4) to inflammation; however, its association with inflammatory cell indices and spirometric parameters in asthma remains unclear, and the potential modifying role of ABO blood group has yet to be ...
Rasha AL-Darraji, Zahraa Abdulaali Al-Mudhafar   +1 more
doaj   +1 more source

The Primary Structure of Piscine (Oncorhynchus mykiss) Retinol-Binding Protein and a Comparison with the Three-dimensional Structure of Mammalian Retinol-Binding Protein

, 1992
1. The primary structures of two variants of rainbow trout (Oncorhynchus mykiss) plasma retinol-binding protein (RBP) were determined and found to be approximately 60% identical with those of both human and Xenopus laevis RBPs.
M. C. ZAPPONI, M. STOPPINI, ZANOTTI, GIUSEPPE, R. BERNI   +3 more
core   +2 more sources