Results 81 to 90 of about 2,787,959 (208)

Ginsenoside CK and retinol on UVA-induced photoaging exert the synergistic effect through antioxidant and antiapoptotic mechanisms

Scientific Reports
Retinol and retinoids can effectively intervene skin aging process, but usually induce skin intolerance. In this study, we aimed to determine the synergistic anti-aging effects of retinol and two retinol derivatives-hydroxypinacolone retinoate (HPR) and ...
Jingyin Zhang, Zhuojun Li, Xiaoping Song, Panpan Cai, Qingchao Liu   +4 more
doaj   +1 more source

Structure-guided screening of FAR-1 antagonists with multi-stage anthelmintic activity

Antimicrobial Agents and Chemotherapy
Fatty acid and retinol binding proteins (FARs) are nematode-specific proteins that orchestrate lipid metabolism, development, and host immune response.
Juan Wen, Wenmin Qi, Jinwei Lv, Yu Lin, Fei Shen, Yu Li, Ziding Zhang, Lihua Xiao, Yaoyu Feng, Dongjuan Yuan   +9 more
doaj   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Levels of cellular retinol-binding proteins in the small intestine of rats during pregnancy and lactation.

Journal of Lipid Research, 1989
The movement and metabolism of vitamin A is dependent on a number of specific carrier proteins. The small intestine contains both cellular retinol-binding protein (type two) (CRBP(II], restricted to the villus-associated enterocytes, and cellular retinol-
T C Quick, D E Ong
doaj   +1 more source

Common epitopes of serum retinol-binding proteins: a study with monoclonal antibodies

, 1990
Monoclonal antibodies were raised against purified chicken retinol-binding protein. These were characterised extensively with respect to their ability to recognize retinol-binding proteins from different species.
Reddy, K, Adiga, PR, Karande, AA
core  

Cell specific localization of retinoid binding proteins and their possible role with retinol transport in the bovine ovary [PDF]

, 2000
The purpose of this study was to characterize the cell specific expression of retinoid binding proteins and determine their possible role in retinol transport in the bovine ovary.
Brown, Jo Alison
core  

Essential Oils From the Fruit of Amomum villosum Lour. Alleviate LPS‐Induced Neuroinflammation by Repressing PI3K‐Akt and MAPK Signaling Pathways

Phytotherapy Research, EarlyView.
Amomum villosum essential oil (AVEO) alleviates LPS‐induced neuroinflammation and cognitive and behavioral dysfunction by suppressing PI3K‐Akt and MAPK signaling pathways, modulating inflammatory responses, and restoring metabolic homeostasis, thereby exerting neuroprotective effects. ABSTRACT Amomum villosum Lour.
Hongjin Wang, Xuetong Li, Zhenhai Huang, Shanshan Luo, Jiyu Weng, Shuanghe Wang, Guofeng Shi, Yixi Zeng, Weishan Wen, Lanyue Zhang, Junxia Zheng, Hui Li   +11 more
wiley   +1 more source

Retinol bound to cellular retinol-binding protein is a substrate for cytosolic retinoic acid synthesis

, 1993
Retinol bound to cellular retinol-binding protein (CRBP) was found to be oxidized to retinoic acid by a soluble activity from calf liver. Cytosolic retinoic acid synthesis from retinol-CRBP was strictly dependent on the exogenous supply of either NAD or ...
G. Scita, D. Cavazzini, G. Mantovani, S. Ottonello, G. L. Rossi   +4 more
core   +1 more source

Retinol and retinol binding protein 4 levels and COVID-19: a Mendelian randomization study

BMC Pulmonary Medicine
Background The Corona Virus Disease 2019 (COVID-19) pandemic has struck globally. Whether the related proteins of retinoic acid (RA) signaling pathway are causally associated with the risk of COVID-19 remains unestablished.
Haixia Wang, Zhiyun Zhang, Li Xie, Kongli Lu, Shuyi Zhang, Shunpeng Xing   +5 more
doaj   +1 more source

Integrative Bioinformatics, Experimental Validation, and Interpretable Machine Learning Reveal Oxyresveratrol‐Mediated Protection Against Cadmium‐Induced Lung Adenocarcinoma‐Related Transcriptional Dysregulation

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd) is a toxic heavy metal strongly implicated in lung adenocarcinoma (LUAD) through mechanisms involving oxidative stress, epigenetic dysregulation, and chronic inflammation. This study aimed to identify Cd‐responsive genes associated with LUAD and to evaluate the protective effects of oxyresveratrol (O‐RES) against Cd‐induced ...
Murat Isıyel, Hamid Ceylan, Yeliz Demir
wiley   +1 more source