Results 131 to 140 of about 2,787,959 (208)

Botanical, Phytochemistry, Pharmacology and Applications of Genus Heracleum: A Review

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
This manuscript presents a comprehensive review of plant species in the genus Heracleum, from botanical classification and distribution to medicinal uses, phytochemistry, pharmacology, and applications, aiming to provide references for further exploration of their therapeutic value and research development.
Nan Zhang, Yuan Li, Zhi‐Yuan Guo, Ye‐Zi Ma, Miao‐Miao Xu, Dong‐Dong Zhang   +5 more
wiley   +1 more source

The primary structure of the human retinol‐binding protein [PDF]

FEBS Letters, 1979
Rask, Lars, Anundi, Helena, Peterson, Per A.   +2 more
openaire   +2 more sources

Mechanism of pH-induced Release of Retinol from Retinol-Binding Protein

, 1993
A hypothesis is proposed explaining the mechanism of pH-induced release of retinol from retinol-binding protein (RBP). A number of conservative positively charged side chains located on the retinol-binding face of the RBP molecule are involved in salt ...
A.L. Denesyuk, G. Zanotti, V.E. Bychkova, ZANOTTI, GIUSEPPE, DENESYUK A. I., BYCHKOVA V. E., O.B. Ptitsyn, PTYTSIN O. B.   +7 more
core   +1 more source

Integrative Transcriptomics and Machine Learning Identify Temporal Stress Signatures and Astrocytic Neurocan Associated With Hypothalamic Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Our research journey revealed a clear split: mRNAs track stress stages, while miRNAs sense stress states. We built a validated predictive model from just 6 markers. The star was Ncan—an astrocytic proteoglycan—which restored neuronal nets and eased depression; virtual knockout confirmed its central role in stress networks.
Weihao Zhu, Chenyu Li, Mengting He, Rui Shi, Xia Liu, Weibo Shi, Bin Cong   +6 more
wiley   +1 more source

Population Genomic Analysis in Wild Medaka Populations: Identifying Candidate Loci for Balancing Selection

Ecology and Evolution, Volume 16, Issue 10, October 2026.
We explored genomic signatures of balancing selection and selective sweep in the northern medaka, Oryzias sakaizumii in Japan by performing whole‐genome resequencing of wild individuals. In addition, we reevaluated the population genetic structure and admixture of Oryzias latipes and O.
Shingo Fujimoto, Taijun Myosho, Hirozumi Kobayashi, Hiroaki Aoyama, Iki Murase, Bayu K. A. Sumarto, Mitsuharu Yagi, Taiga Kunishima, Masatoshi Matsunami, Ryosuke Kimura   +9 more
wiley   +1 more source

Essential dynamics of the cellular retinol-binding protein - Evidence for ligand-induced conformational changes

, 1995
The cellular retinol-binding protein (CRBP) is an intracellular retinol carrier protein belonging to a family of hydrophobic ligand-binding proteins, It transports retinol to specific locations in the cell where, for instance, it is esterified for ...
Findlay, J.B.C., van Aalten, D.M.F., Berendsen, H.J.C., Amadei, A   +3 more
core   +1 more source

Characterisation of transthyretin and retinol-binding protein in plasma and cerebrospinal fluid of dogs

, 2006
The aim of this study was to investigate differences in concentrations of vitamin A, transthyretin (TTR) and retinol-binding protein (RBP) between plasma and cerebrospinal fluid (CSF) in dogs. RBP was detected using ELISA, and both RBP and TTR by Western
Schweigert, Florian J, Forterre, Simone, Brunnberg, Leo, Forterre, Franck, Raila, Jens, Schweigert, Florian Johannes (Prof. Dr.), Raila, Jens (Prof. Dr.)   +6 more
core   +1 more source

Integrated Multi‐Omics and Single‐Cell Analyses Implicate NOX4 as an Icariin‐Associated Oxidative Stress Regulatory Node in Gastric Cancer

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
NOX4 represents a candidate icariin‐associated regulatory node in gastric cancer and may contribute to the cellular response to icariin through redox‐related signaling. ABSTRACT Icariin, a prenylated flavonoid glycoside from Epimedium species, is a representative dietary polyphenol with antioxidant, anti‐inflammatory, and antitumor properties.
Na Liang, Junyan Li, Zuchao Luo, Zijuan Song, Liyuan Zhang, Chengyi Zou, Chunming Li, Bochen Pan, Jiawei Yang   +8 more
wiley   +1 more source

High-resolution Structures of Retinol-Binding Protein in Complex with Retinol: pH-induced Protein Structural Changes in the Crystal State

, 2003
The targeted delivery of non-polar ligands by binding proteins to membranes or membrane receptors involves the release of these ligands on or near the plasma membrane of target cells. Because these hydrophobic ligands are often bound inside a deep cavity
CALDERONE V, BERNI, Rodolfo, V. CALDERONE, ZANOTTI G., ZANOTTI, GIUSEPPE, R. BERNI, Calderone, Vito   +6 more
core   +1 more source

A Novel Homozygous Variant Associated With Distinct Clinical Phenotypes of SDR9C7 Nonsyndromic Epidermal Differentiation Disorder in Two Affected Patients From a Consanguineous Saudi Family

Molecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
Whole exome sequencing identified a novel homozygous SDR9C7 variant in two affected patients from a consanguineous Saudi family presenting distinct lamellar ichthyosis phenotypes. ABSTRACT Background Nonsyndromic Epidermal Differentiation Disorders (nEDD) are a group of heterogeneous disorders characterized by scaling and erythema.
Faisal Almalki, Zaker Khoj, Essa Alharbi, Osama Alsharif   +3 more
wiley   +1 more source