Results 91 to 100 of about 5,652,471 (282)

Hepatic retinol secretion and storage are altered by dietary CLA: common and distinct actions of CLA c9,t11 and t10,c12 isomers[S]

open access: yesJournal of Lipid Research, 2009
Conjugated linoleic acid (CLA) is a polyunsaturated fatty acid obtained from ruminant products. Previous studies in rats and pigs showed that a dietary equimolar mixture of c9,t11 and t10,c12 CLA isomers induces changes in serum and tissue levels of ...
Berenice Ortiz   +5 more
doaj   +1 more source

Binding specificities of cellular retinol-binding protein and cellular retinol-binding protein, type II.

open access: yesJournal of Biological Chemistry, 1987
Cellular retinol-binding protein (CRBP) and cellular retinol-binding protein, type ii (CRBP(II] are cytoplasmic proteins that bind trans-retinol as an endogenous ligand. These proteins are structurally similar having greater than 50% sequence homology. Employing fluorescence, absorbance, and competition studies, the ability of pure preparations of CRBP(
P N, MacDonald, D E, Ong
openaire   +2 more sources

Retinol Binding Protein [PDF]

open access: yesJournal of Parenteral and Enteral Nutrition, 2011
Introduction: Burn injury leads to vast changes in both metabolic and inflammatory responses and is associated with increased morbidity and mortality. Insulin resistance (IR) and hyperglycemia are major components of the hypermetabolic response found in burn‐injured patients and subsequently contribute to adverse outcomes.
Robert, Kraft   +5 more
openaire   +2 more sources

Extraction and recombination studies of the interaction of retinol with human plasma retinol-binding protein

open access: yesJournal of Lipid Research, 1972
Methods have been developed for the removal of retinol from human plasma retinol-binding protein (RBP), so as to form the retinol-free apoprotein, and for the recombination of apo-RBP with retinol to again form the holoprotein.
DeWitt S. Goodman, Amiram Raz
doaj   +1 more source

Signaling by retinol and its serum binding protein

open access: yesProstaglandins, Leukotrienes and Essential Fatty Acids, 2014
Vitamin A, retinol, circulates in blood bound to retinol-binding protein (RBP) which, in turn, associates with transthyretin (TTR) to form a retinol-RBP-TTR ternary complex.
N. Noy
semanticscholar   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca   +7 more
wiley   +1 more source

Effects of acute inflammation on plasma retinol, retinol-binding protein, and its mRNA in the liver and kidneys of vitamin A-sufficient rats

open access: yesJournal of Lipid Research, 1996
The acute inflammatory response to tissue injury and infection is associated with low concentrations of plasma retinol and its specific transport proteins, retinol-binding protein (RBP) and transthyretin (TTR).
F J Rosales   +4 more
doaj   +1 more source

Retinoid-binding proteins: similar protein architectures bind similar ligands via completely different ways. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Retinoids are a class of compounds that are chemically related to vitamin A, which is an essential nutrient that plays a key role in vision, cell growth and differentiation. In vivo, retinoids must bind with specific proteins to perform their
Yu-Ru Zhang, Yu-Qi Zhao, Jing-Fei Huang
doaj   +1 more source

Retinol bound to cellular retinol-binding protein is a substrate for cytosolic retinoic acid synthesis

open access: yes, 1993
Retinol bound to cellular retinol-binding protein (CRBP) was found to be oxidized to retinoic acid by a soluble activity from calf liver. Cytosolic retinoic acid synthesis from retinol-CRBP was strictly dependent on the exogenous supply of either NAD or ...
G. Scita   +9 more
core   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

open access: yesPhytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia   +1 more
wiley   +1 more source

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