Results 81 to 90 of about 4,223,808 (257)

Extraction and recombination studies of the interaction of retinol with human plasma retinol-binding protein

open access: yesJournal of Lipid Research, 1972
Methods have been developed for the removal of retinol from human plasma retinol-binding protein (RBP), so as to form the retinol-free apoprotein, and for the recombination of apo-RBP with retinol to again form the holoprotein.
DeWitt S. Goodman, Amiram Raz
doaj   +1 more source

Retinoid-binding proteins: similar protein architectures bind similar ligands via completely different ways. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Retinoids are a class of compounds that are chemically related to vitamin A, which is an essential nutrient that plays a key role in vision, cell growth and differentiation. In vivo, retinoids must bind with specific proteins to perform their
Yu-Ru Zhang, Yu-Qi Zhao, Jing-Fei Huang
doaj   +1 more source

Effects of acute inflammation on plasma retinol, retinol-binding protein, and its mRNA in the liver and kidneys of vitamin A-sufficient rats

open access: yesJournal of Lipid Research, 1996
The acute inflammatory response to tissue injury and infection is associated with low concentrations of plasma retinol and its specific transport proteins, retinol-binding protein (RBP) and transthyretin (TTR).
F J Rosales   +4 more
doaj   +1 more source

Protein mis-folding and human disease

open access: yes, 2010
Serum Amyloid P Component (SAP), a putative molecular chaperone, is a homopentamericplasma protein of 25kDa subunits. It binds to the amyloid fibrils ofmisfolded proteins, which cause amyloidosis in humans. SAP not only stabilizesamyloid fibrils but also
Pal, Mohinder
core   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Polyphenol dietary supplementation prevents inflammation‐induced muscle atrophy in a zebrafish (Danio rerio) model

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Diet‐induced inflammation is a major cause of muscle degeneration impacting human and animal health. Owing to their anti‐inflammatory and antioxidant properties, polyphenols have attracted considerable interest as feed additives.
Graziella Orso   +8 more
wiley   +1 more source

Association of Polyunsaturated Fatty Acids and Incident Glaucoma: The UK Biobank, Multi Omics, and Therapeutic Strategies Study

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Purpose To investigate the associations and causal effects of polyunsaturated fatty acids (PUFAs) with incident glaucoma and identify intervention thresholds and therapeutic strategies. Methods This prospective study included 451,199 glaucoma‐free UK Biobank participants of European ancestry.
Jianming Xu   +7 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

open access: yesPhytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia   +1 more
wiley   +1 more source

Protein-RNA interactions: a structural analysis [PDF]

open access: yes, 2001
A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single ...
Daley, DT   +9 more
core  

Serum Amyloid A is a Retinol Binding Protein that Transports Retinol during Bacterial Infection [PDF]

open access: yes, 2016
Retinol plays a vital role in the immune response to infection, however it remains unclear which proteins mediate retinol transport during infection. Serum amyloid A (SAA) proteins are produced by the liver following acute systemic infection and are ...
Zlatkov, Clare Marie
core   +1 more source

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