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Retinol palmitate against toxicogenic damages of antineoplastic drugs on normal and tumor cells

Chemico-Biological Interactions, 2020
The lack of tissue selectivity of anticancer drugs generates intense collateral and adverse effects of cancer patients, making the incorporation of vitamins or micronutrients into the diet of individuals to reduce side or adverse effects of antineoplastics.
Bahare Salehi   +2 more
exaly   +3 more sources

Levels of retinyl palmitate and retinol in the stratum corneum, epidermis, and dermis of female SKH-1 mice topically treated with retinyl palmitate

Toxicology and Industrial Health, 2006
Retinyl esters are the storage form of vitamin A in skin, and retinyl palmitate (RP) accounts for the majority of the retinyl esters endogenously formed in skin. RP is also obtained exogenously through the topical application of cosmetic and skin care products that contain RP.
Peter Fu, Paul C Howard, Wayne G Wamer
exaly   +3 more sources

Emulsion and Vesicle Formation of Retinol and Retinyl Palmitate with Egg Yolk Phosphatidylcholine

Journal of Colloid and Interface Science, 1995
Abstract Spreading pressure measurements showed that retinyl palmitate (retinol palmitate, ReO-Pal) and egg yolk phosphatidylcholine (PC) were practically immiscible and separated into PC bilayers and ReO-Pal liquid. On the contrary, substantial amounts of retinol (ReOH) were incorporated into PC bilayers.
Tetsurou Handa, Koichiro Miyajima
exaly   +2 more sources

Levels of retinyl palmitate and retinol in stratum corneum, epidermis and dermis of SKH-1 mice

Toxicology and Industrial Health, 2006
Vitamin A (retinol) regulates many biological functions, including epidermal cell growth. Retinyl palmitate (RP) is the major esterified form of retinol and the predominant component of retinoids in the skin; however, how endogenous levels of RP and retinol in the skin are affected by the age of the animal remains unknown.
Peter Fu, Mary Boudreau, Qingsu Xia
exaly   +3 more sources

Reduction of leukemia cell growth in a patient with acute promyelocytic leukemia treated by retinol palmitate

Leukemia Research, 1990
A 67-year-old woman with acute promyelocytic leukemia (APL) showed a marked decrease in leukemic promyelocytes with concomitant maturation of leukemic cells during treatment with retinol palmitate. A culture study in vitro revealed that retinol, which is the main metabolite of retinol palmitate detected in plasma, induced morphological and functional ...
Hiromichi Iwasaki   +2 more
exaly   +3 more sources

Determination of retinol, retinyl palmitate, and retinoic acid in consumer cosmetic products

International Journal of Cosmetic Science, 2010
J. Cosmet. Sci., 60, 485–500 (September/October 2009)SynopsisRetinol and retinyl palmitate are frequently used in cosmetic products. A simple, rapid, and sensitive reversed‐phase high‐performance liquid chromatography (HPLC) method with ultraviolet (UV) detection was developed for the quantitation of retinol, retinyl palmitate, and retinoic
openaire   +2 more sources

Effect of retinyl palmitate supplementation on egg yolk retinol and cholesterol concentrations in quail

British Poultry Science, 2008
1. The purpose of this study was to assess the incorporation of retinol into quail egg yolk and cholesterol concentration in response to supplementation with different quantities of retinyl palmitate (600, 1200, 2400 and 4800 microg). 2. Supplementations were performed weekly for 4 weeks and the yolk retinol was measured using high performance liquid ...
H M M, Ramalho   +4 more
openaire   +2 more sources

Effect of retinol palmitate on ovulation rate and embryo quality in superovulated cattle

Theriogenology, 1995
Abstract We evaluated the influence of administration of retinol palmitate (Vitamin A) on ovulation rate and embryo quality in 48 beef cows superovulated with 2 different doses of FSH. Synchronization of estrus was accomplished by giving 2 injections of prostaglandin F 2α (PGF) 11 d apart.
D.W. Shaw   +3 more
openaire   +1 more source

2: Final Report on the Safety Assessment of Retinyl Palmitate and Retinol

Journal of the American College of Toxicology, 1987
Retinol is the naturally occurring form of vitamin A; Retinyl Palmitate is the ester of Retinol and Palmitic Acid. In acute oral studies, Retinol was slightly toxic to mice, and Retinyl Palmitate was practically nontoxic in mice and rats. Large single doses can be lethal. It is recognized that Retinol is essential for reproduction; however, high intake
openaire   +1 more source

Impact of Retinol Palmitate Overdose on the Erythrocyte Morphology

SSRN Electronic Journal, 2022
Tatiana A. Lomanovskaya   +10 more
openaire   +1 more source

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