Results 71 to 80 of about 31,607 (196)

Effect of Hyperoxia on Retinoid Metabolism and Retinoid Receptor Expression in the Lungs of Newborn Mice. [PDF]

PLoS ONE, 2015
Preterm newborns that receive oxygen therapy often develop bronchopulmonary dysplasia (BPD), which is abnormal lung development characterized by impaired alveologenesis.
Hsing-Jin Chen, Bor-Luen Chiang
doaj   +1 more source

Dual Knockout Models of the Spatially and Functionally Conserved rgra and rgrb Zebrafish Genes Reveal the Requirement of RGR for the Integrity of Cone‐Mediated Photopic Vision, the Photopic Visual Cycle and Bruch's Membrane Morphology

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
This study investigates the role of the vision gene RGR using novel dual knockout zebrafish models. The loss of rgra and rgrb results in zebrafish larvae having reduced visual function and altered retinoid profiles under light but not dark conditions. The OKR phenotype is enhanced under higher light intensities.
Grace Ruddin, Tess McCann, Joanna J. Kaylor, Michelle M. Fox, John D. Fehilly, Rebecca Ward, Adam Faulkner, Ailís L. Moran, Kieran Wynne, Roxana A. Radu, Michael G. Monaghan, Stephen D. Thorpe, Gabriel H. Travis, Breandán N. Kennedy   +13 more
wiley   +1 more source

Associations between Nugent‐bacterial vaginosis and preterm birth and other adverse pregnancy outcomes in rural northwestern Bangladesh

International Journal of Gynecology &Obstetrics, Volume 173, Issue 2, Page 1094-1104, May 2026.
Abstract Objective Bacterial vaginosis, defined by Nugent score (Nugent‐BV), has been associated with preterm birth and other adverse pregnancy outcomes. However, few studies have longitudinally described the associations between Nugent‐BV and adverse pregnancy outcomes at varying times in pregnancy.
Daniel J. Erchick, Susan Tuddenham, Lena Kan, Lee S. F. Wu, Alain B. Labrique, Hasmot Ali, Ethan K. Gough, Mahbubur Rashid, Towfida J. Siddiqua, Subhra Chakraborty, Pawel Gajer, Michael France, Jacques Ravel, Golsa M. Yazdy, Keith P. West, Parul Christian   +15 more
wiley   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, Volume 13, Issue 21, 13 April 2026.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Mycomeal as a Functional and Sustainable Protein Alternative to Soybean Meal in Saline Tilapia Hybrid Fry (Oreochromis spilurus ♂ × O. niloticus ♀) Diets

Aquaculture, Fish and Fisheries, Volume 6, Issue 2, April 2026.
ABSTRACT This study examined how well mycomeal (rice bran fermented with Volvariella volvacea) can serve as a sustainable replacement for soybean meal (SBM) in the diets of saline‐tolerant hybrid tilapia fry (Oreochromis spilurus × Oreochromis niloticus, SpiN) over a 60‐day feeding trial.
Precious Victoriano‐Blancia, Mark Henry F. De Leon, Vyenge Erre D. Gayosa, Rex Ferdinand M. Traifalgar, Carmelo del Castillo, Sanny David P. Lumayno, Mary Grace C. Sedanza, Mary Jessa Bell B. Pagapulan, Dinah Grace D. Bienes, Angeline T. Eliseo   +9 more
wiley   +1 more source

The Role of Chemopreventive Agents in the Management of Oral Potentially Malignant Disorders and Oral Cancer: A Narrative Review

Cancer Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is a common and aggressive cancer sometimes subsequent to oral potentially malignant disorders (OPMDs). Notwithstanding progress in surgical, radiotherapeutic, and chemotherapeutic interventions, survival rates for OSCC continue to be inadequate and are associated with significant functional ...
Lana Sayal, Omar hamadah, Eyad Chatty, Anas Abdo, Sana Aghbari, Ali Munasser, Amirah Alnour   +6 more
wiley   +1 more source

A Comprehensive Review of Acne Treatments: Unpacking the Chemical Structures and Effective Bioactive Compounds

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background and Aims Acne vulgaris is a frequent skin disorder, affecting a large part of the population worldwide, and strongly influencing not only the physical but also the mental aspects of health. The choice of therapy for acne vulgaris is a very difficult one because the multifactorial causality of the disease and interindividual ...
Mobina Tajdari, Setare Abolghasemi, Elham Khanniri, Maryam Bayanati, Rahil Hakimimofrad, Mohammad Mahboubi‐Rabbani   +5 more
wiley   +1 more source

Retinol esterification in Sertoli cells by lecithin-retinol acyltransferase [PDF]

, 1989
Esterification of retinol occurs during the metabolism of vitamin A in the testis. An acyl- CoA:retinol acyltransferase (ARAT) activity has been described for microsomes isolated from testis homogenates. That activity was also observed here in microsomal
Shingleton, Janet L, Ong, David E, Skinner, Michael K   +2 more
core   +1 more source

Cost‐Efficiency and Cost‐Effectiveness of Alternative Bouillon Fortification Programs: Evidence for Burkina Faso, Nigeria, and Senegal

Annals of the New York Academy of Sciences, Volume 1556, Issue 1, February 2026.
Achieving dietary adequacy in vitamin A, zinc, and/or folate can save child‐lives. Different amounts and combinations of micronutrients have different costs and different effects on child mortality. This study presents ten bouillon fortification options for Nigeria.
Stephen A. Vosti, Michael Jarvis, Lauren Thompson, Emily Becher, Maguette Beye, Faith Ishaya, Karim Koudougou, Reina Engle‐Stone, Katherine P. Adams   +8 more
wiley   +1 more source

Vitamin A combined with retinoic acid increases retinol uptake and lung retinyl ester formation in a synergistic manner in neonatal rats

Journal of Lipid Research, 2006
Vitamin A (VA) is stored in tissues predominantly as retinyl esters (REs), which provide substrate for the production of bioactive retinoids. Retinoic acid (RA), a principal metabolite, has been shown to induce postnatal lung development.
A. Catharine Ross, Namasivayam Ambalavanan, Reza Zolfaghari, Nan-qian Li   +3 more
doaj   +1 more source