Results 31 to 40 of about 14,977 (211)

Retinol Esterification Activity Contributes to Retinol Transport in Stellate Cells.

open access: yesCell Structure and Function, 1999
The mechanisms of retinol transport and accumulation in hepatic stellate cells (HSC) remain to be elucidated. Our previous studies suggested that retinol esterification activity, particularly lecithin:retinol acyltransferase (LRAT) activity, in liver retinoid metabolism is important to elucidate the relationship between retinol uptake by HSC and the ...
T, Matsuura   +3 more
openaire   +3 more sources

Production of functional human vitamin A transporter/RBP receptor (STRA6) for structure determination. [PDF]

open access: yesPLoS ONE, 2015
STRA6 is a plasma membrane protein that mediates the transport of vitamin A, or retinol, from plasma retinol binding protein (RBP) into the cell. Mutations in human STRA6 are associated with Matthew-Wood syndrome, which is characterized by severe ...
Conor J Breen   +5 more
doaj   +1 more source

An ambulance for retinol

open access: yeseLife, 2014
During inflammation, serum amyloid A proteins transport retinol to infected tissues.
Stephanie C Ganal, Andrew J MacPherson
doaj   +1 more source

Retinol and Retinol-Binding Protein Stabilize Transthyretin via Formation of Retinol Transport Complex

open access: yesACS Chemical Biology, 2010
Transthyretin (TTR) is a plasma hormone carrier protein associated with hereditary and senile forms of systemic amyloid disease, wherein slow tetramer disassembly is thought to be an obligatory step. Plasma transport of retinol is carried out exclusively by the retinol-binding protein (RBP), through complexation with transthyretin.
Hyung, Suk-Joon   +2 more
openaire   +4 more sources

Serum and intracellular retinol transport in the equine [PDF]

open access: yesBritish Journal of Nutrition, 1982
1. Serum and intracellular distribution of retinol was determined in equines maintained on four levels of vitamin A intake.2. The form of retinol transported in serum was determined by gel filtration and chromatography to be a complex of retinol bound to a protein of molecular weight (MW) of approximately 20000, which was in turn complexed probably ...
D. Sklan, Susan Donoghue
openaire   +1 more source

Characterization of two post-translationally processed forms of human serum retinol-binding protein: altered ratios in chronic renal failure.

open access: yesJournal of Lipid Research, 1995
Retinol-binding protein (RBP) is the specific blood carrier for the transport of retinol (vitamin A) to target tissues. As the kidney is involved in RBP metabolism, the analysis of RBP species in the serum of patients with chronic renal failure (CRF) was
S. Jaconi   +4 more
doaj   +1 more source

Effects of acute inflammation on plasma retinol, retinol-binding protein, and its mRNA in the liver and kidneys of vitamin A-sufficient rats

open access: yesJournal of Lipid Research, 1996
The acute inflammatory response to tissue injury and infection is associated with low concentrations of plasma retinol and its specific transport proteins, retinol-binding protein (RBP) and transthyretin (TTR).
F J Rosales   +4 more
doaj   +1 more source

Retinol metabolism in rats with low vitamin A status: a compartmental model

open access: yesJournal of Lipid Research, 1990
A compartmental model was developed to describe the metabolism of vitamin A in rats with low vitamin A status maintained by a low dietary intake of vitamin A (approximately 2 micrograms retinol equivalents/day).
KC Lewis, MH Green, JB Green, LA Zech
doaj   +1 more source

Transcriptome shifts triggered by vitamin A and SCD genotype interaction in Duroc pigs

open access: yesBMC Genomics, 2022
Background The composition of intramuscular fat depends on genetic and environmental factors, including the diet. In pigs, we identified a haplotype of three SNP mutations in the stearoyl-coA desaturase (SCD) gene promoter associated with higher content ...
Emma Solé   +6 more
doaj   +1 more source

Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands

open access: yesJournal of Lipid Research, 2021
Present in the small intestine, cellular retinol binding protein 2 (CRBP2) plays an important role in the uptake, transport, and metabolism of dietary retinoids.
Josie A. Silvaroli   +6 more
doaj   +1 more source

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