Results 61 to 70 of about 14,977 (211)

Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development.

PLoS ONE, 2020
BackgroundCytochrome P450 1b1 (Cyp1b1) deletion and dietary retinol deficiency during pregnancy (GVAD) affect perinatal liver functions regulated by Srebp.
Meghan Maguire, Michele Campaigne Larsen, Chad M Vezina, Loredana Quadro, Youn-Kyung Kim, Sherry A Tanumihardjo, Colin R Jefcoate   +6 more
doaj   +1 more source

Multifunctional lipid-based nanocarriers with antibacterial and anti‐inflammatory activities for treating MRSA bacteremia in mice

Journal of Nanobiotechnology, 2021
Background Bacteremia-induced sepsis is a leading cause of mortality in intensive care units. To control a bacterial infection, an immune response is required, but this response might contribute to organ failure.
Chia-Chih Liao, Huang-Ping Yu, Shih-Chun Yang, Ahmed Alalaiwe, You-Shan Dai, Fu-Chao Liu, Jia-You Fang   +6 more
doaj   +1 more source

Associations Between Microbial Depletion and Autonomic Dysregulation in Binge‐Eating Disorder

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The interplay between the gut microbiome and autonomic nervous system remains unexplored in binge‐eating disorder (BED). We aimed to explore specific microbial alterations in BED and examine their potential association with cardiac vagal tone as a distinct bio‐behavioral phenotype.
Shuang Liang, Esben Strodl, Leanne Barron, Matthew Bambling, Luis Vitetta   +4 more
wiley   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source

Identification of SNPs in Cellular Retinol Binding Protein 1 and Cellular Retinol Binding Protein 3 Genes and Their Associations with Laying Performance Traits in Erlang Mountainous Chicken [PDF]

Asian-Australasian Journal of Animal Sciences, 2014
CRBP1 (cellular retinol binding protein 1) and CRBP3 (cellular retinol binding protein 3), are important components of the retinoid signaling pathway and take part in vitamin A absorption, transport and metabolism.
Yan Wang, Li-Hua Xiao, Xiao-Ling Zhao, Yi-Ping Liu, Qing Zhu   +4 more
doaj   +1 more source

Vitamin A transport and the transmembrane pore in the cell-surface receptor for plasma retinol binding protein. [PDF]

PLoS ONE, 2013
Vitamin A and its derivatives (retinoids) play diverse and crucial functions from embryogenesis to adulthood and are used as therapeutic agents in human medicine for eye and skin diseases, infections and cancer.
Ming Zhong, Riki Kawaguchi, Mariam Ter-Stepanian, Miki Kassai, Hui Sun   +4 more
doaj   +1 more source

Retinol transport system in cattle and purification of retinol-binding protein from bovine serum.

The Japanese Journal of Veterinary Science, 1989
Retinol transport system in cattle was investigated, followed by the purification and characterization of bovine serum retinol-binding protein (RBP). Gel filtration of serum from cow produced two retinol peaks, peak 1 and 2. The major, peak 1 having higher molecular weight corresponded to the retinol peak from human serum which consisted of RBP and ...
MIYAMOTO, Toru, KATOH, Norio, MOTOI, Yoshiko, OHASHI, Tsutai, NAGASAWA, Shigeyoshi, SHIMBAYASHI, Koichi   +5 more
openaire   +3 more sources

Blood Biomarkers of Helicobacter pylori‐Infected Chronic Gastritis in Active Versus Stable Phases: A Clinical Indicator Analysis Combined With Proteomic and Metabolomic Investigations

iMetaMed, EarlyView.
Combining clinical data with serum proteomics and metabolomics, the HGB–CAPZB–acetic acid model was developed as a potential diagnostic index to distinguish the active and stable stages of Helicobacter pylori‐infected chronic gastritis, and the related mechanism was explored through multi‐omics.
Tiantong Jiang, Zhen Ma, Yang Li, Shaoli Wang, Yanjiao Zhang, Lei Song, Xianyu Li, Zhen Liu   +7 more
wiley   +1 more source

Retinol-binding protein 4 in skeletal and cardiac muscle: molecular mechanisms, clinical implications, and future perspectives

Frontiers in Cell and Developmental Biology
Retinol-binding protein 4 (RBP4) has emerged as a critical adipokine involved in the pathophysiology of metabolic and cardiovascular diseases. Beyond its classical role in retinol transport, RBP4 influences insulin resistance, inflammation, lipid ...
Kangzhen Zhang, Lijuan Wang, Wei Gao, Rong Guo   +3 more
doaj   +1 more source

Metabolism of retinol-binding protein and vitamin A during hypervitaminosis A in the rat

Journal of Lipid Research, 1975
Vitamin A is normally transported in plasma as retinol bound to a specific protein, retinol-binding protein (RBP). Detailed studies were conducted to examine the effects of excess vitamin A on the plasma concentration and metabolism of RBP, and to obtain
A.K. Mallia, J.E. Smith, D.W. Goodman
doaj   +1 more source