Results 101 to 110 of about 344,007 (291)
Animal Models and Experimental Medicine, EarlyView.We investigated the therapeutic potential and mechanism of chrysin in experimental diabetic retinal disease. Using a streptozotocin (STZ)‐induced diabetic mouse model and high‐glucose‐stimulated BV2 microglia, we revealed chrysin‐responsive pyroptosis‐associated signatures and identified GBP3 as a regulated node.
Qun Liu +9 more
wiley +1 more source
Malarial retinopathy in adult: a case report
The Pan African Medical Journal, 2017 Although widely reported in children, the malarial retinopathy has rarely been described in adults. We observed a case in the department of ophthalmology at the pediatric and gynecology-obstetrics Yaoundé Hospital.
Chantal Ngoune Nanfack +4 more
doaj +1 more source
Diabetic retinopathy: current understanding, mechanisms, and treatment strategies.
JCI Insight, 2017 Diabetic retinopathy (DR) causes significant visual loss on a global scale. Treatments for the vision-threatening complications of diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) have greatly improved over the past decade ...
E. Duh, Jennifer K. Sun, Alan W. Stitt
semanticscholar +1 more source
Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome
Annals of Neurology, EarlyView.Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca +24 more
wiley +1 more source
Intravitreal aflibercept injection in Indian eyes with retinopathy of prematurity
Indian Journal of Ophthalmology, 2019 Purpose: To study the efficacy of intravitreal Aflibercept, an anti Vascular Endothelial Growth factor, (anti-VEGF) in Retinopathy of Prematurity (ROP).
Vasumathy Vedantham
doaj +1 more source
Journal of Applied Polymer Science, EarlyView.PLA and PCL ocular implants prepared by tape casting and electrospinning provide sustained dexamethasone release with distinct release profiles governed by polymer type and processing method. The relationship between polymer structure, degradation behavior, and drug release demonstrates the potential of these fabrication techniques for controlled ...
Renata Bochanoski +6 more
wiley +1 more source
The Pan African Medical Journal, 2018 INTRODUCTION: increased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban ...
Oscar Onyango +7 more
doaj +1 more source
Microglia and Inflammatory Responses in Diabetic Retinopathy
Frontiers in Immunology, 2020 Diabetic retinopathy is a vision-threatening disease affecting neurons and microvasculature of the retina. The development of this disease is associated with the action of inflammatory factors that are connected to the activation of microglial cells, the
Urbanus Muthai Kinuthia +2 more
semanticscholar +1 more source
A simple risk stratification for time to development of sight-threatening diabetic retinopathy. [PDF]
, 2013 OBJECTIVE: The American Diabetes Association and the English NHS Diabetic Eye Screening Program recommend annual screening for diabetic retinopathy (DR) with referral to ophthalmology clinics of patients with sight-threatening DR (STDR).
Taylor, David J. +15 more
core +1 more source
Arthritis &Rheumatology, EarlyView.Objective Hydroxychloroquine (HCQ) nonadherence in systemic lupus erythematosus (SLE) stemming from decision complexities can be improved with shared decision‐making (SDM) tools clarifying benefits and harms. This study aimed to develop and evaluate HCQ‐SAFE, a pictogram‐based SDM tool during SLE visits.
Caroline Packee +8 more
wiley +1 more source