Results 81 to 90 of about 290,153 (304)
Frontiers in Chemistry, 2020 As a key cytokine mediator of inflammation, interleukin-1β (IL-1β) binds to the IL-1 receptor (IL-1R) and activates various downstream signaling mediators, including NF-κB, which is required for immune vigilance and cellular protection.
Azade Geranurimi +14 more
doaj +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021 Introduction The retina and brain exhibit similar pathologies in patients diagnosed with neurodegenerative diseases. The ability to access the retina through imaging techniques opens the possibility for non‐invasive evaluation of Alzheimer's disease (AD)
Jennifer Ngolab +19 more
doaj +1 more source
Intracameral Injection of Bevacizumab for the Treatment of Neovascular Glaucoma [PDF]
, 2011 Purpose: To assess the duration of the effect of intracameral bevacizumab in patients presenting with rubeosis iridis and neovascular glaucoma (NVG). Methods: Retrospective analysis of 24 consecutive eyes of 24 patients with decompensated NVG (> 21 mm Hg)
Haritoglou, Christos +3 more
core +1 more source
Advanced Science, EarlyView.A deep comprehension of biomolecular phenomena at interfaces is significant with their fundamental and practical importance. Our experimental and theoretical investigations reveal that specific amino acids (glutamic acid and aspartic acid) exhibit an orientational coupling with liquid crystals, which can recognize and optically report the interfacial ...
Yena Choi +10 more
wiley +1 more source
A Patient Centered Intervention to Promote Primary Care Based Screening for Diabetic Retinopathy [PDF]
, 2018 Diabetic Retinopathy is the leading cause of blindness in patient\u27s age 25-74 in the world. Onset of disease is insidious and early intervention is the only way to reduce morbidity.
Earle, William B
core +1 more source
Long-term glycemic variability and risk of adverse outcomes: a systematic review and meta-analysis [PDF]
, 2015 OBJECTIVE: Glycemic variability is emerging as a measure of glycemic control, which may be a reliable predictor of complications. This systematic review and meta-analysis evaluates the association between HbA1c variability and micro- and macrovascular ...
Catherine Gorst +18 more
core +1 more source
Advanced Science, EarlyView.In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang +19 more
wiley +1 more source
Malarial retinopathy in adult: a case report
The Pan African Medical Journal, 2017 Although widely reported in children, the malarial retinopathy has rarely been described in adults. We observed a case in the department of ophthalmology at the pediatric and gynecology-obstetrics Yaoundé Hospital.
Chantal Ngoune Nanfack +4 more
doaj +1 more source
Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study. [PDF]
, 2017 Results from observational studies examining dyslipidemia as a risk factor for diabetic retinopathy (DR) have been inconsistent. We evaluated the causal relationship between plasma lipids and DR using a Mendelian randomization approach.
Asian Genetic Epidemiology Network Consortium +43 more
core +1 more source