Results 11 to 20 of about 331,837 (303)

High Glucose-Mediated Tyrosine Nitration of PI3-Kinase: A Molecular Switch of Survival and Apoptosis in Endothelial Cells

Antioxidants, 2018
Diabetes and hyperglycemia are associated with increased retinal oxidative and nitrative stress and vascular cell death. Paradoxically, high glucose stimulates expression of survival and angiogenic growth factors.
Sally L. Elshaer, Tahira Lemtalsi, Azza B. El-Remessy   +2 more
doaj   +1 more source

Neurodegenrative changes in retina of rats with chronic epileptic syndrome under conditions of treatment with niacin-oxy-ethylidene-phosphonate germanate (MIGU-4)

Journal of Ophthalmology, 2023
Background: Epilepsy is accompanied by neurodegenerative changes, particularly those in the retina. Elucidation of the mechanisms of retinal alterations in a model of epileptic syndrome may allow for the development of new approaches to pharmacological ...
N. Al-Nadawi, V.I. Kresyun
doaj   +1 more source

Laser treatment in diabetic retinopathy [PDF]

, 2007
Diabetic retinopathy is a leading cause of visual impairment and blindness in developed countries due to macular edema and proliferative diabetic retinopathy (PDR). For both complications laser treatment may offer proven therapy: the Diabetic Retinopathy
Akduman L, Aljoscha S. Neubauer, Arend O, Bandello F, Benson WE, Chew EY, Davies N, Ferris, Ferris F, Friberg TR, Gabel VP, Gallemore RP, Giovannini A, Gupta V, Hainsworth DP, Jaffe GJ, Kinyoun J, Klein R, Kroll P, Ladas ID, Laursen ML, Lee CM, Lewis H, Luttrull JK, Maeshima K, Michael W. Ulbig, Neubauer AS, Parolini B, Puliafito CA, Sanchez-Tocino H, Schatz H, Shahidi M, Shimura M, Ulbig MR, Ulbig MW, Ulbig MW, Xu X   +36 more
core   +1 more source

Ultrastructure of neurovascular changes in human diabetic retinopathy [PDF]

, 2018
The previous concept regarding diabetic retinopathy assigned a primary role to hyperglycemia-induced microvascular alterations, while neuronal and glial abnormalities were considered to be secondary to either ischemia or exudation.
Artico, Marco, Biró, Zsolt, Fehér, János, Micera, Alessandra, Orlando, Maria Patrizia, Scuderi, Gianluca, Spoletini, Maria Luisa, Taurone, Samanta, Turchetta, Rosaria, Varsányi, Balázs   +9 more
core   +1 more source

Dengue Virus Infection of Human Retinal Müller Glial Cells

Viruses, 2023
Retinopathy is a recently recognized complication of dengue, affecting up to 10% of hospitalized patients. Research on the pathogenesis has focused largely on effects of dengue virus (DENV) at the blood–retinal barrier.
Genevieve F. Oliver, Liam M. Ashander, Abby C. Dawson, Yuefang Ma, Jillian M. Carr, Keryn A. Williams, Justine R. Smith   +6 more
doaj   +1 more source

Autoantibodies against retinal proteins in paraneoplastic and autoimmune retinopathy [PDF]

, 2004
BACKGROUND: Autoimmune retinal degeneration may occur in patients who present with sudden or, less commonly, subacute loss of vision of retinal origin, associated with an abnormal ERG, through the action of autoantibodies against retinal proteins.
AH Milam, B Lei, CE Thirkill, DM Jacobson, G Adamus, G Adamus, G Adamus, G Adamus, G Adamus, G Adamus, G Adamus, G Ren, G Tezel, Gaoying Ren, Grazyna Adamus, H Ohguro, H Ohguro, I Maruyama, JB Mizener, JL Keltner, JL Keltner, JL Keltner, JR Heckenlively, MA Murphy, MJ Potter, MR Stanford, MS Savchenko, R Peek, R Peek, Richard G Weleber, SM Whitcup, YH Yoon   +31 more
core   +3 more sources

The Clinical Influence after Implementation of Convolutional Neural Network-Based Software for Diabetic Retinopathy Detection in the Primary Care Setting

Life, 2021
Deep learning-based software is developed to assist physicians in terms of diagnosis; however, its clinical application is still under investigation.
Yu-Hsuan Li, Wayne Huey-Herng Sheu, Chien-Chih Chou, Chun-Hsien Lin, Yuan-Shao Cheng, Chun-Yuan Wang, Chieh Liang Wu, I.-Te Lee   +7 more
doaj   +1 more source

Replication study: Development and validation of deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs [PDF]

, 2018
Replication studies are essential for validation of new methods, and are crucial to maintain the high standards of scientific publications, and to use the results in practice.
Bongo, Lars Ailo, Møllersen, Kajsa, Voets, Mike   +2 more
core   +3 more sources

Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option? [PDF]

, 2014
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell ...
Chuluyan, Hector Eduardo, Gallo, Juan Eduardo Maria, Ortiz, Gustavo Alfredo, Salica, Juan Pablo   +3 more
core   +1 more source

Pregnancy and Its Effect on the Progression of Diabetic Retinopathy

McGill Journal of Medicine, 2020
N ...
Jeff Van Impe
doaj   +1 more source