Results 31 to 40 of about 290,153 (304)
Frontiers in Medicine, 2021 Objective: To detect retinal involvement in coronavirus disease 2019 (COVID-19) patients in acute and convalescent phase by their fundus screening.Methods: In a prospective, cross-sectional, observational study (July–November 2020), 235 patients (142 ...
Reema Bansal +14 more
doaj +1 more source
Indian Journal of Endocrinology and Metabolism, 2013 Aims: To detect the risk factors of diabetes mellitus (DM) and cardiovascular complications in subjects with impaired fasting glucose (IFG). Materials and Methods: One hundred and twenty three subjects with proved IFG in Zanjan Healthy Heart Study (2002 ...
Faranak Sharifi +4 more
doaj +1 more source
Beta-adrenergic agonist protects retinal pigment epithelium against hydroxycholoroquine toxicity via cAMP-PKA signal pathway [PDF]
International Journal of Ophthalmology, 2020 AIM: To test our hypothesis that activation of protein kinase A (PKA) signal pathway by β-adrenergic agonist plays an important role in the protecting of cultured retinal pigment epithelial (RPE) cells against the hydroxychloroquine (HCQ) toxicity ...
Ruihua Zhang, Dan-Ning Hu, Richard Rosen
doaj +1 more source
Medicine, 2010 Diabetic retinopathy is the leading cause of blindness in the working-age population in the UK. Despite the available treatments, many patients present late in the course of the disease when treatment is more difficult. If diabetic retinopathy is detected, tightening of the modifiable risk factors (e.g.
openaire +3 more sources
Oman Journal of Ophthalmology, 2016 Organophosphates have rarely been reported to cause various ocular sequelae including retinal degeneration. Retinal manifestations have been rarely reported and poorly characterized.
Hang Pham +6 more
doaj +1 more source
Open Veterinary Journal, 2023 Background: Although ocular findings in diabetic patients are well described, prevalence data for those is unknown. Aim: To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus.
Francisco Cantero +3 more
doaj +1 more source
Microvascular Disease with Heart Failure with Reduced and Preserved Ejection Fraction in Patients with Type 2 Diabetes [PDF]
, 2020 Aims: Identification of patients with type 2 diabetes (T2D) at increased risk of incident heart failure (HF) beyond traditional risk factors such as prior myocardial infarction (MI) might allow selection of patients who would benefit from preventative ...
Doney, Alexander +5 more
core +2 more sources
Autophagy Impairment in Retinal Ganglion Cells Following Hypoglycemia in Mice
Cells(1) Background: Diabetic retinopathy (DR), caused by hypo- and hyperglycaemia, is the leading cause of blindness. Hypoglycemia induces endoplasmic reticulum stress and retinal cell death in mice, and low-glucose conditions induce macroautophagy/autophagy
Daria Fresia +4 more
doaj +1 more source
Functional deficits precede structural lesions in mice with high-fat diet-induced diabetic retinopathy [PDF]
, 2016 Obesity predisposes to human type 2 diabetes, the most common cause of diabetic retinopathy. To determine if high-fat diet–induced diabetes in mice can model retinal disease, we weaned mice to chow or a high-fat diet and tested the hypothesis that diet ...
Bligard, Gregory W +5 more
core +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source