Results 31 to 40 of about 192,232 (293)
Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells
Frontiers in Cell and Developmental Biology, 2021 Perinatal exposure to starvation is a risk factor for development of severe retinopathy in adult patients with diabetes. However, the underlying mechanisms are not completely understood.
Türküler Özgümüs +5 more
doaj +1 more source
Beta-adrenergic agonist protects retinal pigment epithelium against hydroxycholoroquine toxicity via cAMP-PKA signal pathway [PDF]
International Journal of Ophthalmology, 2020 AIM: To test our hypothesis that activation of protein kinase A (PKA) signal pathway by β-adrenergic agonist plays an important role in the protecting of cultured retinal pigment epithelial (RPE) cells against the hydroxychloroquine (HCQ) toxicity ...
Ruihua Zhang, Dan-Ning Hu, Richard Rosen
doaj +1 more source
Journal of Current Ophthalmology, 2019 To report a case of solar retinopathy due to inadvertent exposure to the sun while piloting a drone without protective eyewear.A 29-year-old male underwent a complete eye exam including optical coherence tomography (OCT) of the macula.Bilateral juxtafoveal outer retinal microcystic cavities present on OCT consistent with solar retinopathy.With the ...
Victoria Rohring +4 more
openaire +3 more sources
Journal of Family Medicine and Primary Care, 2020 Purpose: Association of peripheral neuropathy with diabetic retinopathy is known but the relationship of preclinical neuropathy with various grades of retinopathy is not well documented.
Devika Joshi +2 more
doaj +1 more source
Chronic complications in newly diagnosed patients with Type 2 diabetes mellitus in India
Indian Journal of Endocrinology and Metabolism, 2014 Background: Prevalence of diabetes is on an increase in India, currently there is limited nation-wide data regarding the prevalence of chronic complications in diabetic patients at diagnosis.
Aravind Sosale +6 more
doaj +1 more source
Takayasu Arteritis Presenting as Bilateral Ocular Ischemic Syndrome
Vascular Specialist International, 2020 A 26-year-old female came in with progressive blurring of vision. She had developed memory loss and complained of headache, significant weight loss, and exertional left calf pain after prolonged walking.
Ramon B. Larrazabal +2 more
doaj +1 more source
Retinopathy of Prematurity [PDF]
Pediatric Clinics of North America, 1987 ROP is a challenging disease of the decade of the 1980s. Answers, even partial answers, to many of its questions may provide information bearing on those same questions in other blinding vascular retinopathies, such as diabetes and sickle cell disease. Answers more clearly defining the role of oxygen, ventilation, antioxidants, blood transfusions, and ...
openaire +6 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source