Results 51 to 60 of about 192,232 (293)
A Holistic Approach to a Rare Case of Kearns–Sayre Syndrome
Journal of Medical Sciences, 2020 Mitochondrial disease, which was previously considered as a rare clinical entity, is presently identified as a significant cause of a broad range of muscle, cardiac, neurologic, as well as endocrine disorders.
Saurav Mittal +3 more
doaj +1 more source
Open Veterinary Journal, 2023 Background: Although ocular findings in diabetic patients are well described, prevalence data for those is unknown. Aim: To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus.
Francisco Cantero +3 more
doaj +1 more source
Advanced Science, Volume 12, Issue 28, July 24, 2025.In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang +10 more
wiley +1 more source
The Pan African Medical Journal, 2018 INTRODUCTION: increased survival of preterm babies in sub-saharan Africa has held to an increasing prevalence of Retinopathy of prematurity (ROP). This study was done to determine the ROP prevalence in a hospital with advanced neonatal care in urban ...
Oscar Onyango +7 more
doaj +1 more source
Retinopathy of Prematurity [PDF]
North Carolina Medical Journal, 2017 Retinopathy of prematurity (ROP) is a vasoproliferative retinal disorder unique to premature infants. As premature births increase in many areas of the world, ROP has become a leading cause of childhood blindness. A better understanding of the pathogenesis of ROP, adherence to strict screening guidelines, and evolution of treatment options have reduced
openaire +2 more sources
Advanced Science, EarlyView.A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana +10 more
wiley +1 more source
Journal of Medical and Scientific Research, 2022 Background: Hypertension is a major health issue in India and it has led to increasing incidences of target organ damage including hypertensive retinopathy (HR). Many factors like platelet activation show influence in levels of HR. Mean platelet volume (
Mali NH, Amita K, Rakshitha HB, Sanjay M
doaj +1 more source
Post‐Translational Modifications in Cilia and Ciliopathies
Advanced Science, EarlyView.This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
Is there an association between mean platelet volume and diabetic retinopathy? A case-control study
Caspian Journal of Internal Medicine, 2021 Background: To the aim of this study was to evaluate the association between mean platelet volume (MPV) and diabetic retinopathy (DR). Methods: Patients with diabetes mellitus (DM) referred to Ophthalmology Clinic of Rohani Teaching Hospital in Babol ...
Seyed Ahmad Rasoulinejad
doaj
Advanced Science, EarlyView.This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren +11 more
wiley +1 more source