Results 141 to 150 of about 47,608 (324)

Urinary extracellular vesicle miRNA signature reflects pancreatic islet stress in type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
Urinary ECV miRNAs show a distinct dysregulation signature in T2D with strong diagnostic performance. This signature mirrors molecular changes across pancreatic islets, blood, liver, and adipose tissue, with the strongest concordance in islets, linking it to β‐cell stress. Overall, they represent a non‐invasive, mechanistically informative biomarker of
Md. Zubbair Malik   +10 more
wiley   +1 more source

Validation of the ST1RE risk engine in Chinese with type 1 diabetes and comparison with the JADE, RECODe, and UKPDS risk scores

open access: yesJournal of Diabetes Investigation, EarlyView.
Steno Type 1 Risk Engine (ST1RE) and the Joint Asia Diabetes Evaluation (JADE) coronary heart disease equation showed best performance with good calibration for predicting CVD in Chinese with Type 1 diabetes. The Risk Equations for Complications of Type 2 Diabetes (RECODe), the UKPDS Outcomes Model version 2 (UKPDS‐OM2), and SCORE2‐Diabetes had poor ...
Andre KH Ma   +13 more
wiley   +1 more source

Retinopathy of Prematurity and MicroRNAs

open access: yesBiomedicines
Retinopathy of Prematurity (ROP), a leading cause of blindness in preterm infants, arises from dysregulated angiogenesis and inflammation. Without timely intervention, ROP can progress to severe outcomes, including dense fibrovascular plaques and retinal detachment.
Albanese, Giuseppe Maria   +8 more
openaire   +4 more sources

Development and production of allogeneic cord blood‐derived red blood cell concentrates for transfusion to extremely preterm neonates, the All‐Cord study

open access: yesTransfusion, EarlyView.
Abstract Background Extremely preterm neonates often require red blood cell (RBC) transfusions derived from adult donors. These transfusions introduce adult hemoglobin into a neonatal hematopoietic system dominated by fetal hemoglobin (HbF), shifting the oxygen‐dissociation curve and increasing oxygen delivery to immature tissues.
Jip H. van Daelen   +8 more
wiley   +1 more source

A study of retinopathy of prematurity at a tertiary care centre in Western Maharashtra [PDF]

open access: yesAl Ameen Journal of Medical Sciences
Background: Retinopathy of prematurity (ROP) is a vaso-proliferative retinal disease which can cause blindness if not diagnosed early. The various risk factors associated with ROP other than pre mature birth and low birth weight are high flow oxygen ...
Ajit K. Joshi   +4 more
doaj  

High myopia following unilateral cryocoagulation for threshold retinopathy of prematurity [PDF]

open access: yes, 2016
Despite the proven benefit of cryotherapy in the management of threshold retinopathy of prematurity (ROP), it was shown leading to ocular adverse effects. A male infant was born at 28 week of gestation with a birth weight of 1200 g.
Lo, Yee Lin   +2 more
core  

Cord blood red cell concentrates for preterm neonate transfusion: Insights from the multicenter BORN trial

open access: yesTransfusion, EarlyView.
Abstract Background The BORN trial suggested that using cord blood‐red blood cells (CB‐RBCs) to transfuse severely preterm neonates significantly improves clinical outcomes compared to standard adult donor RBCs (A‐RBC). Study Design and Methods The study illustrates CB‐RBC concentrate production and inventory management across nine CB banks ...
Claudio Pellegrino   +38 more
wiley   +1 more source

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