Results 71 to 80 of about 2,780,590 (362)

SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy

Advanced Science, EarlyView.
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong, Guangyu Liang, Huimin Yu, Jiaqi Li, Ruohong Wang, Xiaohong Ma, Ziqing Zhou, Yin Zhao, Fei Sun, Xufang Sun   +9 more
wiley   +1 more source

A predictive score for retinopathy of prematurity in very low birth weight preterm infants [PDF]

, 2011
Aims This study describes the development of a score based on cumulative risk factors for the prediction of severe retinopathy of prematurity (ROP) comparing the performance of the score against the birth weight (BW) and gestational age (GA) in order to ...
A Aggarwal, A Hellstrom, A Hellstrom, A Patz, AL Hard, C Gilbert, C Lofqvist, C Lofqvist, DK Wallace, Early Treatment for Retinopathy of Prematurity Cooperative Group, EZ Martinez, G Binenbaum, G U Eckert, GE Quinn, HL Chen, J B Fortes Filho, J Chen, JB Fortes Filho, JB Fortes Filho, JB Fortes Filho, JB Fortes Filho, JB Fortes Filho, JI Hagadorn, K Allegaert, LE Smith, M Eriksson, M Maia, MS Brown, O Aydemir, P Manzoni, R S Procianoy, S Fluckiger, SE Brooks, Thomas Aaberg, VA Shah   +34 more
core   +1 more source

Survivorship of Individuals With Double Heterozygosity for Achondroplasia and Type 2 Collagenopathy

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Historically, double heterozygosity, or a diagnosis of two separate, dominant genetic conditions, was often thought to be lethal in individuals with autosomal dominant skeletal dysplasias. In previously published studies of individuals with dual dysplasia diagnoses of achondroplasia and type 2 collagenopathy, infants died of respiratory ...
Valerie R. Schwartz, Andrea Schelhaas, Angela L. Duker, Ricki S. Carroll   +3 more
wiley   +1 more source

The Effect of Treated Retinopathy of Prematurity in Premature Infants on Ocular Structural Outcomes [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2023
Background and Objective: Retinopathy of prematurity is a complex developmental disease of retinal vessels in premature infants. Improvements in preterm care services are associated with an increased risk of advanced stages of retinopathy of prematurity.
Z Nezamdoost, A Bayat, M Arish, P Najafi, M Mahjoob   +4 more
doaj  

Peribulbar block combined with general anesthesia in babies undergoing laser treatment for retinopathy of prematurity: a retrospective analysis [PDF]

Revista Brasileira de Anestesiologia, 2018
Background and objectives Currently there is no agreement regarding which one is the most adequate anesthetic technique for the treatment of retinopathy of prematurity.
Daniela Filipa Rodrigues Pinho, Cátia Real, Leónia Ferreira, Pedro Pina   +3 more
doaj   +3 more sources

Early Detection of Retinopathy of Prematurity (ROP) in Retinal Fundus Images Via Convolutional Neural Networks [PDF]

arXiv, 2020
Retinopathy of prematurity (ROP) is an abnormal blood vessel development in the retina of a prematurely-born infant or an infant with low birth weight. ROP is one of the leading causes for infant blindness globally. Early detection of ROP is critical to slow down and avert the progression to vision impairment caused by ROP.
arxiv  

Telemedicine for Retinopathy of Prematurity.

Telemedicine journal and e-health, 2020
Background: Retinopathy of prematurity (ROP) is a disease of the retinal vasculature that remains a leading cause of childhood blindness worldwide despite improvements in the systemic care of premature newborns.
Christopher J Brady, Samantha L. D'Amico, J. Campbell   +2 more
semanticscholar   +1 more source

Endothelial nitric oxide synthase gene T-786C and 27-bp repeat gene polymorphisms in retinopathy of prematurity [PDF]

, 2008
PURPOSE: Retinopathy of prematurity (ROP), which is associated with abnormal retinal vessel development, is the leading cause of visual loss in preterm infants.
Borgulya, G, Fekete, A, Rusai, K, Szabó, AJ, Szebeni, B, Tulassay, T, Vannay, A, Vásárhelyi, B   +7 more
core   +1 more source

Brazilian guidelines proposal for screening and treatment of retinopathy of prematurity (ROP) [PDF]

, 2007
Retinopathy of prematurity is one of the main causes of childhood blindness. Worldwide, there are more than 50,000 children blind due to retinopathy of prematurity. Visual impairment is a consequence of retinal detachment.
Florêncio, Telma, Fortes Filho, João Borges [UNIFESP], Gianini, Nicole, Graziano, Rosa Maria, Moraes, Nilva [UNIFESP], Nakanami, Célia Regina [UNIFESP], Zin, Andrea   +6 more
core   +3 more sources

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

BMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen, Ying Yao, Yan Zhang, Xinyu Shi, Ling Bai, Yang Zhong, Yan Zhang, Kun Zhang   +7 more
wiley   +1 more source