Results 61 to 70 of about 6,473 (203)

Макуларна ретиношиза и нејзината семиотска важност [PDF]

, 2015
Вовед. Поимот ретиношиза означува раздвојување во слоевите на неуроретината. Може да се случи во периферните делови на ретината, но исто така и во регионот на макула лутеа кога зборуваме за макуларна ретиношиза.
Blazevska, Karolina, Golubovik, Milena, Isjanovski, Igor, Tatesi, Bekim   +3 more
core  

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

Acta Ophthalmologica, Volume 103, Issue 8, Page 998-1009, December 2025.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao, Linxin Wei, Huan Chen, Yan Luo, Youxin Chen, Zhikun Yang   +5 more
wiley   +1 more source

Analysis of Peripapillary Atrophy Using Spectral Domain Optical Coherence Tomography [PDF]

, 2010
Objective To study retinal morphologic changes around the optic disc in patients with peripapillary atrophy (PPA) with high-resolution spectral domain optical coherence tomography (SD OCT). Design Cross-sectional, retrospective analysis. Participants
Duker, Jay S., Fujimoto, James G., Manjunath, Varsha, Shah, Heeral   +3 more
core   +1 more source

AAV Gene Therapy Drug Development and Translation of Engineered Ocular and Neurotropic Capsids: A Systematic Review Using Natural Language Processing

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Natural AAV serotypes often lack specificity and efficiency, leading to off‐target effects and a low therapeutic index. To overcome these limitations of naturally occurring serotypes, there has been a keen interest in the field to engineer novel capsids to enhance tissue and cell‐specific targeting, resulting in a high number of published ...
Chinaza Agbim, Heng‐Yi Wu, Chloe Kim, Elizabeth Mutter‐Rottmayer, Shraddha Sadekar, Milica Markovic   +5 more
wiley   +1 more source

Clinical features of a toddler with bilateral bullous retinoschisis with a novel RS1 mutation

American Journal of Ophthalmology Case Reports, 2017
Purpose: To report the clinical and genetic findings of a male toddler who presented bilateral bullous retinoschisis with a novel RS1 mutation. Observations: This is an observational case report of a patient referred to our hospital with esotropia.
Satoshi Katagiri, Shin Tanaka, Tadashi Yokoi, Takaaki Hayashi, Emiko Matsuzaka, Kazuko Ueda, Tomoyo Yoshida-Uemura, Akira Arakawa, Sachiko Nishina, Kazuaki Kadonosono, Noriyuki Azuma   +10 more
doaj   +1 more source

Bullous X linked retinoschisis: clinical features and prognosis [PDF]

, 2018
BACKGROUND/AIMS: A subset of patients with X linked retinoschisis (XLRS) have bullous schisis cavities in the peripheral retina. This study describes the characteristics and prognosis of the bullous form of XLRS.
Fahim, A, Hinds, A-M, Michaelides, M, Moore, AT, Wong, SC   +4 more
core  

Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates. [PDF]

, 2020
Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery and ...
Chung, Sook Hyun, Mollhoff, Iris N, Nguyen, Uyen Tu, Noronha, Glenn, Taraborelli, Donna, Thomasy, Sara M, Yiu, Glenn, Yoo, Jesse   +7 more
core  

A fast protocol for photodynamic therapy in exudative choroidal circumscribed hemangioma: Early laser irradiance after end of verteporfin infusion

Acta Ophthalmologica, Volume 103, Issue 7, Page 831-841, November 2025.
Abstract Purpose The aim of the study is to compare the risk of first‐line photodynamic therapy (PDT) failure according to the PDT protocol performed in patients with exudative choroidal circumscribed hemangioma (CCH). Methods We retrospectively included patients from 11 European centres in France, Italy and Denmark.
Paul Dubar, Thibaud Mathis, Emilie Hucteau, Juliette Thariat, Maxime Nhari, Célia Maschi, Carsten Faber, Jens Folke Kiilgaard, Carlo Mosci, Catherine Favard, Sarah Tick, Anh‐Minh Nguyen, Jean‐Pierre Caujolle, Marie‐Noëlle Delyfer, Laurence Rosier   +14 more
wiley   +1 more source

Expression Profiling Analysis Reveals Key MicroRNA– mRNA Interactions in Early Retinal Degeneration in Retinitis Pigmentosa [PDF]

, 2018
PURPOSE. The aim of this study was to identify differentially expressed microRNAs (miRNAs) that might play an important role in the etiology of retinal degeneration in a genetic mouse model of retinitis pigmentosa (rd10 mice) at initial stages of the ...
Anasagasti, Ander, Barandika, Olatz, Caffarel, María M., Ezquerra-Inchausti, Maitane, López de Munain Arregui, Adolfo José, Muñoz-Culla, Maider, Otaegui Bichot, David, Ruiz-Ederra, Javier   +7 more
core   +2 more sources

Retinal Viral Gene Therapy: Impact of Route of Administration on Serious Adverse Events—A Systematic Review

Clinical &Experimental Ophthalmology, Volume 53, Issue 8, Page 967-985, November 2025.
ABSTRACT Background To explore the prevalence of serious adverse events (SAEs) associated with retinal viral gene therapy and to examine trends influencing SAE occurrences in human gene therapy surgeries and pre‐clinical animal trials. Methods Literature review was performed to identify peer‐reviewed human and animal studies relevant to viral gene ...
Aubrey Berger, Ciera D. Johnson, Alan D. Marmorstein, Brittni A. Scruggs   +3 more
wiley   +1 more source