Results 81 to 90 of about 5,586 (206)

Case Report: Carbonic anhydrase inhibitor brinzolamide dramatically improved the morphology and also function of a patient with RS1 mutation

Frontiers in Pharmacology
X-linked retinoschisis (XLRS) is an inherited retinal disease caused by mutations in the RS1 gene, which encodes retinoschisin, a protein essential for maintaining the retinal structure during development.
Yue Ren, Yue Ren, Shu Liu, Shu Liu, Jia Rong, Di Wang, Miao Diao, Yaqi Zhang, Shimiao Tian, Mingxin Shang, Chuqiao Song, Yan Guan, Zhuoshi Wang, Zhuoshi Wang, Jijing Pang, Jijing Pang, Jijing Pang   +16 more
doaj   +1 more source

Retinal Detachment in a Combined Case of Stickler Syndrome and X-Linked Retinoschisis

, 2017
A 12-year-old boy presented with a total rhegmatogenous retinal detachment and a giant retinal tear in the right eye. Clinical examination, optical coherence tomography, and fundus images showed an optically empty vitreous, lattice degeneration, and ...
Mehta, Neesurg S, Audina M. Berrocal, McClellan, Andrew J, Read, Sarah P, Sarah P. Read, Berrocal, Audina M, Neesurg S. Mehta, Yannuzzi, Nicolas A, Nicolas A. Yannuzzi, Andrew J. McClellan, Ryan Young, Young, Ryan   +11 more
core   +1 more source

Retinoschisis transposition following a retinal detachment repair

, 2015
Objective: The authors have observed this phenomenon of translocation of the schisis cavity in a few previous cases and aim to report this unusual finding.
McVeigh, K, Haynes, Richard J., McVeigh, Katherine, Keller, Johannes, Keller, J, Haynes, RJ   +5 more
core   +1 more source

Pars plana vitrectomy in patients with myopic macular retinoschisis

, 2014
Background/aims To report the outcomes of patients undergoing pars plana vitrectomy (PPV) for myopic macular retinoschisis. Methods Retrospective, non-randomised case series of patients who underwent PPV for myopic macular retinoschisis.
Chang, Jonathan S, Chang, Stanley, Smiddy, William E, Engelbert, Michael, Flynn, Harry W, Shane, Anita R   +5 more
core   +1 more source

Immune landscape in children with X-linked retinoschisis

BMC Immunology
Background X-linked retinoschisis is a retinovitreal disorder primarily affecting males, starting in childhood. Over time, patients experience deterioration of vision due to the lack of retinoschisin-1 function. In clinical trials performing intravitreal
Ying Hsu, Giulia Del Valle, Sarah Stanley, Brianna Lobeck, Sergei I. Syrbu, Christine Sinkey, Christopher R. Fortenbach, Alina Dumitrescu, Arlene V. Drack   +8 more
doaj   +1 more source

In vivo sectional imaging of the retinal periphery using conventional optical coherence tomography systems

Indian Journal of Ophthalmology, 2012
Optical coherence tomography (OCT) has transformed macular disease practices. This report describes the use of conventional OCT systems for peripheral retinal imaging.
Abhishek Kothari, V Narendran, V R Saravanan   +2 more
doaj   +1 more source

A proposed mechanism influencing structural patterns in X-linked retinoschisis and stellate nonhereditary idiopathic foveomacular retinoschisis

, 2019
© 2018, The Royal College of Ophthalmologists. Objective: To explore the structural differences between X-linked retinoschisis (XLR) and stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) using swept-source optical coherence tomography ...
Sherman, J., Talia R. Kaden, Leong, B. C., Fragiotta, S., Kaden, T. R., Serena Fragiotta, Sherry J. Bass, Lawrence A. Yannuzzi, Bass, S. J., Jerome Sherman, Belinda C. S. Leong, Freund, K. B., Yannuzzi, L. A., K. Bailey Freund   +13 more
core   +2 more sources

Retinoschisis in the Setting of Coats’ Disease

, 2014
This is a report of a 5-year-old boy who presented with an exudative retinopathy consistent with Coats' disease. Optical coherence tomography confirmed the concurrent presence of retinoschisis in the same eye, adjacent to the areas of exudation and ...
Ditte J. Hess, Audina M. Berrocal, Berrocal, Audina M, Jonathan H. Tzu, Yannuzzi, Nicolas A, Nicolas A. Yannuzzi, Tzu, Jonathan H, Hess, Ditte J   +7 more
core   +1 more source

Retinal detachment associated with the splice site mutation c.53-1G>A in the gene: A case report and review of the literature

SAGE Open Medical Case Reports
Retinoschisin protein is mainly produced in the retina, with minimal expression in other tissues. It is located on the surface of the photoreceptor inner segments and bipolar cells.
Jia Meng, Shanjun Cai, Gang Su
doaj   +1 more source

Micropulse transscleral cyclophotocoagulation in the treatment of autosomal recessive bestrophinopathy combined with angle closure glaucoma: a case report

Frontiers in Medicine
BackgroundAutosomal recessive bestrophinopathy (ARB) comprises remarkable retinal dystrophy characterized by yellowish subretinal lesions scattered in the posterior pole and is always accompanied with refractory angle-closure glaucoma (ACG).
Jinkun Liu, Yingying Xue, Weiyi Huang, Yuhong Wang   +3 more
doaj   +1 more source