Results 61 to 70 of about 4,063 (173)

Multilevel Genetic and Functional Assessment of an ARR3 Frameshift Variant in Early‐Onset High Myopia

International Journal of Genomics, Volume 2026, Issue 1, 2026.
Background Early‐onset high myopia (eoHM) is a highly heritable ocular disorder, with pathogenic variants in the X‐linked ARR3 gene (which encodes cone arrestin) being associated with a female‐limited form of eoHM. However, the clinical manifestations of early truncating variants in ARR3 and their potential impact on the classic sex‐limited pattern ...
Yadi Li, Fengwu Teng, Qin Zhu, Shulan Cui, Wenfu Yang, Pengcheng Ma, Neetu Rawal   +6 more
wiley   +1 more source

Genetic Association Study Between Refractive Error–Related Genes and High Myopia in the Chinese Han Population

Journal of Ophthalmology, Volume 2026, Issue 1, 2026.
Background Refractive errors are the leading cause of visual impairment and blindness globally. High myopia (HM) poses significant risks of severe ocular complications and blindness. 12 SNPs, including rs580839, have been associated with refractive errors in European and Asian populations, but their roles in Chinese cohorts remain unexplored.
Jianxin Liu, Weijiang Liao, Chunbao Xie, Xinyu Wang, Yukai Gong, Chunchun Yang, Fang Hao, Yin Yang, Liang Zou, Yi Shi, Jiayu Meng, Lingxi Jiang, Shweta Negi   +12 more
wiley   +1 more source

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

Acta Ophthalmologica, Volume 103, Issue 8, Page 998-1009, December 2025.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao, Linxin Wei, Huan Chen, Yan Luo, Youxin Chen, Zhikun Yang   +5 more
wiley   +1 more source

Identifying rhegmatogenous detachments in bullous retinoschisis with optical coherence tomography studies

American Journal of Ophthalmology Case Reports, 2017
Purpose: To demonstrate a novel technique for capturing optical coherence tomography images of peripheral retina and its application in identifying rhegmatogenous retinal detachments within bullous retinoschisis.
Josh O Wallsh, Ron P. Gallemore
doaj   +1 more source

AAV Gene Therapy Drug Development and Translation of Engineered Ocular and Neurotropic Capsids: A Systematic Review Using Natural Language Processing

Clinical and Translational Science, Volume 18, Issue 12, December 2025.
ABSTRACT Natural AAV serotypes often lack specificity and efficiency, leading to off‐target effects and a low therapeutic index. To overcome these limitations of naturally occurring serotypes, there has been a keen interest in the field to engineer novel capsids to enhance tissue and cell‐specific targeting, resulting in a high number of published ...
Chinaza Agbim, Heng‐Yi Wu, Chloe Kim, Elizabeth Mutter‐Rottmayer, Shraddha Sadekar, Milica Markovic   +5 more
wiley   +1 more source

In vivo sectional imaging of the retinal periphery using conventional optical coherence tomography systems

Indian Journal of Ophthalmology, 2012
Optical coherence tomography (OCT) has transformed macular disease practices. This report describes the use of conventional OCT systems for peripheral retinal imaging.
Abhishek Kothari, V Narendran, V R Saravanan   +2 more
doaj   +1 more source

Optical coherence tomography and congenital retinoschisis: three case reports

Revista Brasileira de Oftalmologia
Congenital retinoschisis is an X-linked recessive inherited disease. It causes the splitting of the retina’s neurosensory layers from the remaining of the sensory retina, presenting itself as a “stellate” or “bicycle-wheel” maculopathy, vitreous ...
Cláudia Gallicchio Domingues, Walter Turra Bocchese, Chrissiê Fianco Capitanio, Maiara Vendramin Pezzolatto, Davi da Silva Costi   +4 more
doaj   +1 more source

Isolated traumatic aniridia after trabeculectomy in a pseudophakic eye

Indian Journal of Ophthalmology, 2014
This is a single case report of an elderly patient who had blunt trauma in an eye that had phacoemulsification and two trabeculectomies. She had good vision with a well-functioning bleb before the trauma.
Subashini Kaliaperumal, Robin Troutbeck, Wallop Iemsomboon, Adrian Farinelli   +3 more
doaj   +1 more source

Intraoperative challenges and management of fibrovascular membrane with tractional retinoschisis in proliferative diabetic retinopathy

BMC Ophthalmology
Background In severe Proliferative Diabetic Retinopathy (PDR), fibrovascular membrane (FVM) causes macular tractional retinal detachment (MTRD) which threatens vision and eventually leads to blindness.
Akihiko Shiraki, Nobuhiko Shiraki, Susumu Sakimoto, Kazuichi Maruyama, Takatoshi Maeno, Kohji Nishida   +5 more
doaj   +1 more source

Bullous retinoschisis

Indian Journal of Ophthalmology, 2019
Sabia Handa, Atul Arora, Nitin Kumar, Reema Bansal   +3 more
openaire   +3 more sources