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Pharmacokinetics of retinyl palmitate and retinol after intramuscular retinyl palmitate administration in severe malaria

Clinical Science, 2000
Retinol (vitamin A alcohol) is an accepted adjunctive treatment in infections such as measles. There is also indirect evidence from in vitro, animal and human studies that retinol supplementation may be beneficial in severe malaria. There have, however, been no studies that have examined the pharmacokinetics of acute retinol supplementation in severe ...
T M, Davis   +6 more
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Retinyl palmitate in water environment

Journal of Photochemistry and Photobiology B: Biology, 1997
Abstract The interaction between retinyl palmitate molecules and their environment in binary water- p -dioxane solvent (at different molar ratios of water to p -dioxane) was studied. The absorption, fluorescence emission and fluorescence excitation spectra were analysed. In this binary solvent, the interaction between retinyl palmitate molecules and
Regina Drabent   +3 more
openaire   +1 more source

Retinyl palmitate hydrolase activity in human liver

The American Journal of Clinical Nutrition, 1992
Retinyl palmitate hydrolase (RPH) activity was studied in human liver after the optimal conditions of the assay in normal human liver homogenates were determined. The mean activity was 118 +/- 66 nmol.min-1.g-1 (mean +/- SD) protein in liver homogenates from six children and seven adults; no correlation was found between liver hydrolase activity and ...
M S, Mourey, O, Amédée-Manesme
openaire   +2 more sources

Allergic contact dermatitis from retinyl palmitate in polycaprolactone

Contact Dermatitis, 2007
Udgivelsesdato: 2007 ...
Clemmensen, Anders   +2 more
openaire   +3 more sources

Retinyl palmitate hydrolase activity in the bovine retina

Biochemical and Biophysical Research Communications, 1986
Retinyl palmitate hydrolase (RPH) activity of bovine tissues was estimated from retinol formation following incubation of tissue homogenates with all-trans retinyl palmitate. The quantity of retinol produced in the incubation mixture was analyzed by high-performance liquid chromatography.
A T, Tsin, K W, Lam
openaire   +2 more sources

Retinyl palmitate flexible polymeric nanocapsules: Characterization and permeation studies

Colloids and Surfaces B: Biointerfaces, 2010
Polymeric nanocapsules with elastic characteristics were prepared by the pre-formed polymer interfacial deposition method. The system consists of an oily core of retinyl palmitate with Span 60 and a polymeric wall of poly(D,L-lactide) (PLA). A narrow size distribution (215 nm, P.D.I. 0.10) was showed by dynamic light scattering (DLS) analyses. Particle
Zaine, Teixeira   +9 more
openaire   +2 more sources

Physiological Role of Retinyl Palmitate in the Skin

2007
The skin is similar to other organs in how it absorbs, stores, and metabolizes vitamin A. However, because of the anatomical location of skin and the specialized physiological roles it plays, there are ways in which the skin is rather unique. The stratified structure of the epidermis results from the orchestration of retinoid-influenced cellular ...
Peter P, Fu   +5 more
openaire   +2 more sources

Cytosol binding of retinyl palmitate and palmitic acid in pigment epithelium and retina

Experimental Eye Research, 1981
Abstract A 6S protein which binds [ 14 C]retinyl palmitate is present in the soluble fraction (cytosol) of the pigment epithelium but not the retina. There is no binding of [ 14 C]retinyl palmitate by the 2S retinol receptor in either the pigment epithelium or the retina. [ 14 C]Palmitic acid is bound to a peak at 6S in pigment epithelial cytosol and
B, Wiggert   +3 more
openaire   +2 more sources

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