Results 111 to 120 of about 16,728 (252)

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Development of a Retrieval-Augmented Generation (RAG) Chatbot [PDF]

Ovidius University Annals: Economic Sciences Series
Our research presents a Retrieval-Augmented Generation (RAG) chatbot designed for intelligent document-based question answering. Built with Streamlit as the front-end, the application integrates LLaMA2 models hosted on Replicate, alongside a document ...
Simona-Vasilica Oprea , Adela Bâra
doaj  

Gap‐Free Information Transfer in 4D‐STEM via Fusion of Complementary Scattering Channels

Advanced Science, EarlyView.
Fused Full‐Field STEM (FF‐STEM) is introduced as a 4D‐STEM imaging modality that combines direct ptychography with tilt‐corrected dark‐field reconstruction in a single acquisition. Fourier‐space fusion using Wiener‐type spectral weighting closes the low‐frequency contrast gap inherent to bright‐field methods, delivering gap‐free, dose‐efficient, near ...
Shengbo You, Georgios Varnavides, Sagar Khavnekar, Nikita Palatkin, Sihan Shao, Mingjian Wu, Daniel Stroppa, Darya Chernikova, Baixu Zhu, Ricardo Egoavil, Stefano Vespucci, Dileep Krishnan, Xingchen Ye, Florian K. M. Schur, Erdmann Spiecker, Philipp Pelz   +15 more
wiley   +1 more source

AI-enabled software requirements specification for banking chatbot systems

New Trends in Computer Sciences
Software Requirements Specification plays an important role in the success of software development projects by providing clear, structured, and consistent documentation of requirements.
Ansu Mary Jacob, Jolanta Miliauskaitė
doaj   +1 more source

Retrieval Augmented Comic Image Generation

CoRR
We present RaCig, a novel system for generating comic-style image sequences with consistent characters and expressive gestures. RaCig addresses two key challenges: (1) maintaining character identity and costume consistency across frames, and (2) producing diverse and vivid character gestures.
Yunhao Shui, Xuekuan Wang, Feng Qiu, Yuqiu Huang, Jinzhu Li, Haoyu Zheng, Jinru Han, Zhuo Zeng, Pengpeng Zhang, Jiarui Han, Keqiang Sun   +10 more
openaire   +2 more sources

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

Advanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr, Reuben Rideaux, Amaya J. Fox, David R. Lightfoot, Jason Tangen, Jason B. Mattingley, Shane E. Ehrhardt   +6 more
wiley   +1 more source

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

Advanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su, Xitao Wang, Musen Li, Guanhua Qin, Shunbo Hu, Tong‐Yi Zhang   +5 more
wiley   +1 more source

Case Study on Understanding the Power of Retrieval Augmented Generation (RAG) [PDF]

Journal of Systemics, Cybernetics and Informatics
This paper explores how Generative AI is changing with the use of Retrieval-Augmented Generation (RAG). RAG helps improve Artificial Intelligence (AI) systems by making them more capable, efficient and accurate.
Venkata Jaipal Reddy Batthula, Richard S. Segall, Sreejith Sivasubramony   +2 more
doaj  

An Agent-Based RAG Architecture for Intelligent Tourism Assistance: The Valencia Case Study

Tourism and Hospitality
The contemporary digital landscape overwhelms visitors with fragmented and dynamic information, complicating travel planning and often leading to decision paralysis.
Andrea Bonetti, Adrián Salcedo-Puche, Joan Vila-Francés, Xaro Benavent-Garcia, Emilio Fernández-Vargas, Rafael Magdalena-Benedito, Emilio Soria-Olivas   +6 more
doaj   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source