Results 81 to 90 of about 1,650,736 (328)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Explainable self-supervised learning for medical image diagnosis based on DINO V2 model and semantic search

Scientific Reports
Medical images have become indispensable for decision-making and significantly affect treatment planning. However, increasing medical imaging has widened the gap between medical images and available radiologists, leading to delays and diagnosis errors ...
Alaa Hussien, Abdelkareem Elkhateb, Mai Saeed, Nourhan M. Elsabawy, Alaa Ebraheem Elnakeeb, Nora Elrashidy   +5 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

An ECC with error detection and against side channel attacks for resource constrained devices

Journal of King Saud University: Computer and Information Sciences
As more devices are integrated into the Internet of Things (IoT) ecosystem, accurate and efficient information transmission between resource-constrained equipment has become particularly important.
Jun Ye, Zewen Yang
doaj   +1 more source

An affect-based video retrieval system with open vocabulary querying [PDF]

, 2010
Content-based video retrieval systems (CBVR) are creating new search and browse capabilities using metadata describing significant features of the data.
Hau Chan, Ching, Jones, Gareth J.F.
core  

Assessment of an oocyte retrieval simulation training program for residents: from training to clinical practice [PDF]

, 2023
Pierre‐Emmanuel Bouet, Amélie Watelet, Benoît Brilland, Hady El Hachem, Pascale May‐Panloup   +4 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Applying Science Models for Search [PDF]

, 2011
The paper proposes three different kinds of science models as value-added services that are integrated in the retrieval process to enhance retrieval quality.
Mayr, Philipp, Mutschke, Peter, Petras, Vivien, Schaer, Philipp, Sure, York   +4 more
core   +1 more source

RBIR Based on Signature Graph

, 2015
This paper approaches the image retrieval system on the base of visual features local region RBIR (region-based image retrieval). First of all, the paper presents a method for extracting the interest points based on Harris-Laplace to create the feature ...
Le, Thanh Manh, Van, Thanh The
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source