Results 121 to 130 of about 59,959 (160)

The Serendipitous Discovery of Rollover Cyclometalation: From Unrecognized Observation to Transformative Chemistry

European Journal of Inorganic Chemistry, EarlyView.
Rollover cyclometalation is a distinctive variant of classical cyclometalation where a chelated heterocyclic ligand undergoes internal rotation, releasing one donor atom from coordination and subsequently activating a remote C─H bond with high regioselectivity.
Antonio Zucca, Maria I. Pilo
wiley   +1 more source

Nucleophilic Reactions of Cyclobutenones and the Related 4,4‐Dichlorocyclobutenone Derivatives

European Journal of Organic Chemistry, EarlyView.
Cyclobutenone derivates and their 4,4‐dichloro counterparts have an uninterrupted attention as useful synthons in the synthesis of complex organic molecules. Their nucleophilic reactions remain underexplored. This review brings attention to these reactions, whose outcome is not straightforward.
Sarah J. Wright, Muhluri H. Mthombeni, Songeziwe Ntsimango   +2 more
wiley   +1 more source

Investigation of α‐Silylalcohols as Chiral Umpolung Carbanion Surrogates Through Stereospecific 1,2‐Brook Rearrangement

European Journal of Organic Chemistry, EarlyView.
Deprotonation of chiral α‐silyl secondary alcohols leads to masked polarity‐reversed chiral carbanions through stereospecific 1,2‐Brook rearrangement. In situ trapping with Weinreb amide electrophiles affords α‐hydroxyketones with moderate to excellent enantiospecificity (es).
TyAnn McHenry, Joshua D. Sieber
wiley   +1 more source

Application of Machine Learning Approaches in Electrophoresis—A Comprehensive Review

ELECTROPHORESIS, EarlyView.
This review paper highlights key research on the applications of machine learning tools in electrophoresis. ABSTRACT The electrophoretic technique is widely used to analyze and purify charged molecules based on their size, shape, and charge using an electric field for various applications, including DNA fingerprinting, genetic research, disease ...
Umaeer Al Hammad, Aminul Islam Khan, Prashanta Dutta   +2 more
wiley   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

Epileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron, Laure Salmon, Nicolas Nguyen, Dènahin Toffa, Sami Obaid, Alexis Robin, Dang Khoa Nguyen   +6 more
wiley   +1 more source

Epileptic arousals: A neglected clinical entity

Epilepsia, EarlyView.
Abstract Objective Epileptic arousals (EAs) are seizures characterized solely by arousal from sleep. EAs are unrecognized in current seizure classifications. Their subtle semiology and inconsistently detectable ictal activity in scalp electroencephalography (EEG) complicate differentiation from physiological arousals (PAs). This study characterizes EAs
Lea Fisel, Nóra Pető, Sotirios Kalousios, Nicolas Zabler, Armin Brandt, Peter C. Reinacher, Dieter Riemann, Mohammad F. Khazali, Andreas Schulze‐Bonhage   +8 more
wiley   +1 more source

Prevalence of epilepsy and the burden of underlying causes: Canadian validation of Danish estimates

Epilepsia, EarlyView.
Abstract Objective Recent work has provided population‐based estimates of the prevalence of cause‐specific epilepsy across the lifespan in Denmark. We sought to externally validate these Danish “secondary epilepsy” findings to ascertain consistency across geographic regions.
Marin Anderson, Jakob Christensen, Channa Buxbaum, Jaimie Steinmetz, Nathalie Jette, Samuel Wiebe, Colin B. Josephson   +6 more
wiley   +1 more source

Genetic developmental and epileptic encephalopathies in adulthood: Gaps in evidence and care

Epilepsia Open, EarlyView.
Abstract Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of the most severe epilepsies, characterized by seizure onset and neurodevelopmental delay in infancy or childhood, often with additional neurological and systemic comorbidities.
Alex M. Dudley, Peter Widdess‐Walsh, Christine Linehan, Danielle M. Andrade, Norman Delanty, Patrick B. Moloney   +5 more
wiley   +1 more source

Reframing Technology and Ethics in Corneal Xenotransplantation: A Scoping Review of Standards and Safety in Ophthalmology

Health Care Science, EarlyView.
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha, Moubani Dutta, Agnihiya Bosu   +2 more
wiley   +1 more source

Surgery After Thermal Ablation of Thyroid Nodules: A Systematic Review of Surgical Risk, Strategy and Pathological Findings

Head &Neck, EarlyView.
ABSTRACT Background Thermal ablation is increasingly used for selected thyroid nodules, but some patients subsequently require thyroidectomy. The effect of prior ablation on surgical risk, operative strategy, and histopathology remains unclear. Methods PubMed/MEDLINE, EMBASE, and the Cochrane Library were searched from inception to May 2026 for studies
Francesco Brucchi, Federica Poli, Beatrice Sperotto, Carla Colombo, Laura Fugazzola, Gianlorenzo Dionigi   +5 more
wiley   +1 more source