Results 141 to 150 of about 59,959 (160)

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu   +2 more
wiley   +1 more source

Neutralization of IL‐17A Ameliorates PM2.5‐Induced Cardiac Inflammation and Fibrosis in Rats by Suppressing the TXNIP/NLRP3 Signaling Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Fine particulate matter (PM2.5) pollution is a major environmental risk factor for cardiovascular diseases. Exposure can cause cardiac inflammation and fibrosis. However, whether interleukin‐17A (IL‐17A) contributes to these effects is unclear.
An‐Shuai Ba   +6 more
wiley   +1 more source

Allograft use and fixed suspensory fixation increase revision risk in multiple revision anterior cruciate ligament reconstruction: A Swedish knee ligament registry study

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this study was to assess the association between surgical‐related variables, revision‐free survival and knee injury and osteoarthritis outcome score (KOOS) following multiple revision anterior cruciate ligament reconstruction (mrACLR) using data from a national knee ligament registry.
Felix Conrad Oettl   +7 more
wiley   +1 more source

Single‐Lens Counter‐Focused Ultrashort Laser Pulses for Enhanced Microplasma Formation Inside Silicon

open access: yesLaser &Photonics Reviews, EarlyView.
A polarization‐dependent liquid–crystal spatial light modulator is used to generate coaxial double‐focus laser beams with independently tunable focal separation and intensity. Applied to silicon, this configuration enables counterpropagating pulse interactions using a single focusing element, enhancing nonlinear excitation and achieving near‐critical ...
Niladri Ganguly   +2 more
wiley   +1 more source

Manufacturing Nostalgia in the Digital Age: A Foreverism Perspective

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT Many scholars argue that we are experiencing the era of “retro”—nostalgia‐driven marketing and consumption phenomena reinforced by digital technologies. However, existing research lacks a critical analysis of nostalgia in contemporary markets and of how digital content, tools, and environments transform retro consumption experiences and alter ...
Dinara Davlembayeva   +4 more
wiley   +1 more source

Efficacy of IncobotulinumtoxinA (BoNT‐A) Injections in Upper Limb Task‐Specific and Position‐Dependent Tremors

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Task‐specific tremors (TST) and position‐dependent tremors (PDT) are rare isolated focal tremors that impair fine motor control with few effective treatment options. Although botulinum neurotoxin (BoNT) is effective in other tremor syndromes, its evidence in these tremor subtypes remains limited.
Elizabeth K. Boyd   +3 more
wiley   +1 more source

Monomethylated and Unmethylated FUS Exhibit Increased Binding to Transportin and Distinguish FTLD-FUS From ALS-FUS [PDF]

open access: yesActa Neuropathologica, 2016
Deposition of the nuclear DNA/RNA-binding protein Fused in sarcoma (FUS) in cytosolic inclusions is a common hallmark of some cases of frontotemporal lobar degeneration (FTLD-FUS) and amyotrophic lateral sclero- sis (ALS-FUS).
Daniel Jutzi   +2 more
exaly   +4 more sources

Transportin 1 Accumulates Specifically With FET Proteins but No Other Transportin Cargos in FTLD-FUS and Is Absent in FUS Inclusions in ALS With FUS Mutations [PDF]

open access: yesActa Neuropathologica, 2012
Accumulation of the DNA/RNA binding protein fused in sarcoma (FUS) as inclusions in neurons and glia is the pathological hallmark of amyotrophic lateral sclerosis patients with mutations in FUS (ALS-FUS) as well as in several subtypes of frontotemporal ...
Chiara F Valori   +2 more
exaly   +2 more sources
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Retro-Translocation of Proteins From the Endoplasmic Reticulum Into the Cytosol

Nature Reviews Molecular Cell Biology, 2002
Tom Rapoport, Yihong Ye, Billy Tsai
exaly  

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