Results 111 to 120 of about 101,297 (257)

Safety and effectiveness of voxelotor in individuals with sickle cell disease in the RETRO and PROSPECT US registries. [PDF]

open access: yesBlood Adv
Andemariam B   +11 more
europepmc   +1 more source

De Novo Design of Multivalent α/β‐Peptides Mimicking Transcription Factors Targeting the CBP KIX Domain

open access: yesChemistry – A European Journal, EarlyView.
A modular, de novo α/β‐peptide design strategy allows fine‐tuning of ligand properties, resulting in multivalent ligands that simultaneously target separate binding sites on the protein surface. ABSTRACT Protein‐protein interactions that regulate gene expression in the nucleus are increasingly recognized as potential therapeutic targets but present ...
Márk V. Tresztián   +4 more
wiley   +1 more source

Organocatalytic Formal (3+2+1)‐Cycloaddition of Allenoates, Michael Acceptors, and Carbaldehydes

open access: yesChemistry – A European Journal, EarlyView.
The use of secondary amine Lewis base organocatalysts allows for the unprecedented activation of allenoates for formal (3+2+1)‐cycloadditions with Michael acceptors and aromatic carbaldehydes. ABSTRACT Employing secondary amines as covalently interacting Lewis basic organocatalysts allows for the activation of electron‐deficient allenes (allenoates ...
David Naderer   +5 more
wiley   +1 more source

Product‐Related CSR in the Digital Era: Communication Patterns That Drive Consumer Interactions on Social Media

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT To meet rising sustainability demands, companies increasingly use social media to communicate product‐related CSR initiatives. Consumers' interactions with these messages largely depend on the messages' perceived credibility. However, there remains limited understanding of how firms combine communication characteristics into distinct patterns ...
Judith Derenthal, Waldemar Toporowski
wiley   +1 more source

Psychological Treatment for Pediatric Feeding Disorder (PFD) and Avoidant/Restrictive Food Intake Disorder (ARFID)

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To produce a consensus statement on the psychological treatment of feeding/eating aversions seen in pediatric feeding disorder (PFD) and avoidant/restrictive food intake disorder (ARFID), diagnoses that share common symptoms and psychological mechanisms but have historically been addressed separately in the literature. Method To help
Colleen T. Lukens   +12 more
wiley   +1 more source

Outcomes of Retro Colic Retro Pyloric Roux En Y Hepaticojejunostomy In Biliary Reconstruction

open access: yesJournal of Gandhara Medical and Dental Sciences
OBJECTIVES To assess the effectiveness of retro pyloric Roux-En-Y Hepaticojejunostomy in cases of choledochal cysts and bile duct injuries to reduce complications, such as delayed gastric emptying and acute cholangitis.
Siddique Ahmad   +4 more
doaj  

Change in skeletal muscle mass during systemic cancer treatment: a systematic review and meta-analysis. [PDF]

open access: yesActa Oncol
Svendsen L   +11 more
europepmc   +1 more source

The Dynamics of the Policy Mix and Sectoral Gaps in South Korea's Decarbonization Transition

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT While a coherent policy mix is a fundamental prerequisite for successful energy transitions, existing frameworks predominantly rely on static evaluations. This horizontal approach fails to capture the deep temporal dynamics and physical inertia inherent in socio‐technical regime shifts.
Yong Hwan Kim, Kyung Nam Kim
wiley   +1 more source

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