Results 161 to 170 of about 1,246,243 (313)
A Retrospective Cohort Study of Leptospirosis in Crete, Greece. [PDF]
Ioannou P+6 more
europepmc +1 more source
Spontaneous loss of early pregnancy and risk of ischaemic heart disease in later life: retrospective cohort study [PDF]
Gordon C. S. Smith
openalex +1 more source
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han+16 more
wiley +1 more source
Motor vehicle driver injury and socioeconomic status: a cohort study with prospective and retrospective driver injuries [PDF]
Gary Whitlock
openalex +1 more source
Chen et al. identified a metabolic gene prognostic signature with machine‐learning framework and assessed the prognostic value in independent CRC cohorts. The metabolic signature subtypes are characterized by specific metabolic and proteomic characteristics, and associated with distinct molecular pathway and therapeutic potential.
Hao Chen+12 more
wiley +1 more source
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang+6 more
wiley +1 more source
Interpregnancy interval and risk of preterm birth and neonatal death: retrospective cohort study [PDF]
openalex +1 more source
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen+18 more
wiley +1 more source