Results 241 to 250 of about 3,326,214 (390)

Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study

The Lancet Respiratory Medicine, 2020
L. Piroth, J. Cottenet, A. Mariet, P. Bonniaud, M. Blot, P. Tubert-Bitter, C. Quantin   +6 more
semanticscholar   +1 more source

MALMPS: A Machine Learning‐Based Metabolic Gene Prognostic Signature for Stratifying Clinical Outcomes and Molecular Heterogeneity in Stage II/III Colorectal Cancer

Advanced Science, EarlyView.
Chen et al. identified a metabolic gene prognostic signature with machine‐learning framework and assessed the prognostic value in independent CRC cohorts. The metabolic signature subtypes are characterized by specific metabolic and proteomic characteristics, and associated with distinct molecular pathway and therapeutic potential.
Hao Chen, Ze Wang, Chenglong Sun, Yang Zhong, Yuan Liu, Yikun Li, Tongchao Zhang, Yuan Zhang, Xingyu Zhu, Leping Li, Feifei Teng, Ming Lu, Wei Chong   +12 more
wiley   +1 more source

Aspirin, ibuprofen, and mortality after myocardial infarction: retrospective cohort study [PDF]

, 2003
Jeptha P. Curtis, Yongfei Wang, Edward L. Portnay, Frederick A. Masoudi, Edward P. Havranek, Harlan M. Krumholz   +5 more
openalex   +1 more source

Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness‐Mediated Bimodal PD‐L1/CXCL10 Regulation

Advanced Science, EarlyView.
This study demonstrates that Piezo1 activation enhances FAK‐YAP‐mediated upregulation of PD‐L1 and CXCL10, thereby promoting an immunotherapy‐responsive tumor microenvironment in NSCLC. Cyclic stretch modulates the PD‐L1/CXCL10 response to ECM stiffness, reshaping their expression dynamics.
Tian Zhang, Yuan Li, Bo Cheng, Zhao Xu, Mengjie Liu, Jinteng Feng, Yixue Bai, Yang Yu, Panpan Jiang, Luying Geng, Feng Xu, Hui Guo   +11 more
wiley   +1 more source

Clinical characteristics of behçet's disease in palestine, a retrospective cohort study. [PDF]

BMC Rheumatol
Daraghma A, Baidoun L, Nazzal S, Hattab M, Jalamneh B, Abusalameh M, Hanbali R, Abdoh Q.   +7 more
europepmc   +1 more source

Motor vehicle driver injury and socioeconomic status: a cohort study with prospective and retrospective driver injuries [PDF]

, 2003
Gary Whitlock
openalex   +1 more source

Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study.

The Lancet Respiratory Medicine, 2018
A. Schauwvlieghe, B. Rijnders, N. Philips, Rosanne Verwijs, L. Vanderbeke, C. van Tienen, K. Lagrou, P. Verweij, F. L. van de Veerdonk, D. Gommers, P. Spronk, D. Bergmans, A. Hoedemaekers, E. Andrinopoulou, C. H. van den Berg, N. Juffermans, C. J. Hodiamont, A. Vonk, P. Depuydt, J. Boelens, J. Wauters   +20 more
semanticscholar   +1 more source

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

Advanced Science, EarlyView.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen, Yujie Zhu, Xi Yang, JiangBin Wu, Keyuan Chen, Wuqing Huang, Lu Fang, Qi Zhang, Jie Chen, Jianing Gao, Huanhuan Cao, Meifang Wu, Zhihuang Qiu, Yuling Zhang, Yue Shen, Qiuyu Huang, Zhiyong Lin, Lemin Zheng, Liangwan Chen   +18 more
wiley   +1 more source

Household secondary attack rate of COVID-19 and associated determinants in Guangzhou, China: a retrospective cohort study

Lancet. Infectious Diseases (Print), 2020
Q. Jing, Mingjin Liu, Zhoubing Zhang, L. Fang, Jun Yuan, Anran Zhang, N. Dean, L. Luo, M. Ma, I. Longini, E. Kenah, Ying Lu, Yu Ma, Neda Jalali, Zhicong Yang, Yang Yang   +15 more
semanticscholar   +1 more source

ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy

Advanced Science, EarlyView.
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie, Tianyi Ji, Zixin Wan, Jie Huang, Han Li, Lingjiao Zou, Zhen Yang, Jiarui Li, Yuqi Guan, Lei Ruan, Jinhua Yan, Cuntai Zhang   +11 more
wiley   +1 more source