Results 281 to 290 of about 3,326,214 (390)

Geriatric ocular trauma and mortality: A retrospective cohort study. [PDF]

open access: yesPLoS One
Pham VQ   +6 more
europepmc   +1 more source

A Dynamic Contrast‐Enhanced MRI‐Based Vision Transformer Model for Distinguishing HER2‐Zero, ‐Low, and ‐Positive Expression in Breast Cancer and Exploring Model Interpretability

open access: yesAdvanced Science, EarlyView.
This study develops a Vision Transformer‐based DCE‐MRI model for the non‐invasive classification of HER2 expression in breast cancer, demonstrating robust performance across multicenter cohorts. By integrating transcriptomic analysis, the model reveals immune‐related pathway differences among distinct HER2 expression levels.
Xu Zhang   +13 more
wiley   +1 more source

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

open access: yesAdvanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu   +5 more
wiley   +1 more source

Epidemiological trends of elbow and forearm injuries in high school baseball and softball players

open access: yesJSES Reviews, Reports, and Techniques
Background: Elbow and forearm injuries are common in high school baseball and softball players. Given the trends in overuse and early sport specialization, it may be prudent to provide an updated review of the epidemiological data to aid injury ...
Christopher Frey, MD   +4 more
doaj  

Risk of Thyroid Tumors With GLP-1 Receptor Agonists: A Retrospective Cohort Study. [PDF]

open access: yesDiabetes Care
Morales DR   +30 more
europepmc   +1 more source

Radiomics‐Based Unsupervised Clustering Identifies Subtypes Associated With Prognosis and Immune Microenvironment in Clear Cell Renal Cell Carcinoma: A Multicenter Study

open access: yesAdvanced Science, EarlyView.
This study developed an unsupervised radiomics system integrating CT imaging and multi‐omics data to stratify clear cell renal cell carcinoma into two subtypes with distinct clinical outcomes. Cluster 1 showed lower recurrence risk and active immunity, while Cluster 2 exhibited higher recurrence risk, enriched VHL/KDM5C mutations, immunosuppressive ...
Yusheng Guo   +14 more
wiley   +1 more source

Association Between the Hemoglobin Glycation Index (HGI) and Risk of Diabetic Nephropathy: A Retrospective Cohort Study

open access: yesDiabetes, Metabolic Syndrome and Obesity
Weiyi Zhou,1 Lingyu Zhang,2 Tongqiang Liu1 1Department of Nephrology, The Affiliated Changzhou Second People’s Hospital of Nanjing Medical University, Changzhou Medical Center, Changzhou, Jiangsu, People’s Republic of China; 2Department of Endocrinology,
Zhou W, Zhang L, Liu T
doaj  

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