Results 61 to 70 of about 2,021,769 (367)

Enterococcal periprosthetic joint infection: clinical and microbiological findings from an 8-year retrospective cohort study [PDF]

, 2019
BACKGROUND: Treatment of enterococcal periprosthetic joint infections (PJI) is challenging due to non-standardized management strategies and lack of biofilm-active antibiotics. The optimal surgical and antimicrobial therapy are unknown.
Akgün, Doruk, Perka, Carsten, Renz, Nora, Trampuz, Andrej, Trebse, Rihard   +4 more
core   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Prevalence, associated factors, management and outcomes of hypokalaemia in hospitalised patients at a South African tertiary centre

South African Medical Journal
Background. Hypokalaemia is a common electrolyte disorder encountered in hospitalised patients and is associated with significant morbidity and mortality.
C Burton, M-Y Chothia, A Zemlin, S Lahri
doaj   +1 more source

Estimation of marriage incidence rates by combining two cross-sectional retrospective designs: Event history analysis of two dependent processes [PDF]

Journal of the Indian Statistical Association Vol. 59 No. 1, June 2021, 21-57, 2020
The aim of this work is to develop methods for studying the determinants of marriage incidence using marriage histories collected under two different types of retrospective cross-sectional study designs. These designs are: sampling of ever married women before the cross-section, a prevalent cohort, and sampling of women irrespective of marital status ...
arxiv  

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Retrospective cohort study of the risk of impaired glucose tolerance among shift workers

Scandinavian Journal of Work, Environment & Health, 2012
OBJECTIVES: The aim of this study was to investigate the effect of shift working on the risk of developing impaired glucose tolerance (IGT). METHODS: This study comprised 6413 male employees (5608 daytime workers, 512 3-shift workers and 293 2-shift ...
Ichiro Oyama, Tomohide Kubo, Yoshihisa Fujino, Koji Kadowaki, Masamizu Kunimoto, Kiyoyumi Shirane, Hidetoshi Tabata, Ken Sabanai, Takehiro Nakamura, Shinya Matsuda   +9 more
doaj   +1 more source

Hashimoto’s thyroiditis increases the risk of new-onset systemic lupus erythematosus: a nationwide population-based cohort study

Arthritis Research & Therapy, 2023
Background Previous studies have shown systemic lupus erythematosus (SLE) patients had a significantly higher prevalence of thyroid diseases and hypothyroidism than matched controls, and some case reports showed SLE may occur after Hashimoto’s ...
Hong-Ci Lin, Hsu-Min Chang, Yao-Min Hung, Renin Chang, Hsin-Hua Chen, James Cheng-Chung Wei   +5 more
doaj   +1 more source

Is depression a real risk factor for acute myocardial infarction mortality? A retrospective cohort study [PDF]

, 2019
Background: Depression has been associated with a higher risk of cardiovascular events and a higher mortality in patients with one or more comorbidities.
Baldo, V., Baldovin, T., Bertoncello, C., Buja, A., Casale, P., Cocchio, S., Fonzo, M., Furlan, P.   +7 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Associations of polyunsaturated fatty acids with cardiovascular disease and mortality: a study of NHANES database in 2003–2018

BMC Endocrine Disorders, 2023
Background This study was to explore the association between dietary polyunsaturated fatty acids (PUFAs) consumption and cardiovascular diseases (CVDs), all-cause mortality, and CVD-specific mortality.
Na Zhong, Pengyu Han, Yulin Wang, Chaoyang Zheng   +3 more
doaj   +1 more source