Results 61 to 70 of about 3,484,928 (322)

Clinical and laboratory findings from patients with COVID-19 pneumonia in Babol North of Iran: a retrospective cohort study

Romanian journal of internal medicine = Revue roumaine de medecine interne, 2020
Background. In December 2019, China has experienced an outbreak of novel coronavirus disease 2019 (COVID-19). Coronavirus has now spread to all of the continents.
M. Javanian, M. Bayani, M. Shokri, M. Sadeghi-Haddad-Zavareh, A. Babazadeh, B. Yeganeh, S. Mohseni, R. Mehraein, M. Sepidarkish, Ali Bijani, A. Rostami, M. Shahbazi, Afrooz Monadi Tabari, A. Shabani, J. Masrour-Roudsari, A. Hasanpour, Hossein Emam Gholinejad, Hossein Ghorbani, S. Ebrahimpour   +18 more
semanticscholar   +1 more source

A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United States

Scientific Reports, 2021
Children and adolescents account for ~ 13% of total COVID-19 cases in the United States. However, little is known about the nature of the illness in children.
V. Parcha, Katherine S. Booker, R. Kalra, S. Kuranz, L. Berra, G. Arora, P. Arora   +6 more
semanticscholar   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Elevated blood pressure and hyperuricemia risk: a retrospective cohort study from Wuhu, China

Scientific Reports
Although the relationship between hypertension and hyperuricemia is widely recognized, there is still a relative lack of research on prehypertensive individuals and the individual associations of systolic and diastolic blood pressure with the risk of ...
Yicheng Fang, Grace Tavengana, Huan Wu, Wendan Mei, Chao Jiang, Chenxu Wang, Xia Ren, Jian Hu, Fan Su, Shi Cheng, Xinyu Ma, Tong Wang, Yue Wu, Yufeng Wen   +13 more
doaj   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Analysing referral patterns from a primary dermatological clinic to other medical institutions for further care: A survey on patients with certain skin diseases in Japan

JEADV Clinical Practice
Background Various skin diseases exist; some require specialist treatment. Consequently, patients with these conditions are often referred from primary dermatological clinics to other medical institutions for further secondary or tertiary care.
Daisuke Ueo, Takashi Sakai, Erika Ochiai, Jun Sese, Yutaka Hatano   +4 more
doaj   +1 more source

Critical Transitions in Intensive Care Units: A Sepsis Case Study [PDF]

Scientific Reports, 9(1) (2019), 2019
The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights into the underlying disease-driving mechanisms. In this paper, we propose a computational method based on surprise loss (SL) to discover data-driven indicators of such ...
arxiv   +1 more source

Cluster of COVID-19 in northern France: A retrospective closed cohort study

medRxiv, 2020
Background: The Oise department in France has been heavily affected by COVID-19 in early 2020. Methods: Between 30 March and 4 April 2020, we conducted a retrospective closed cohort study among pupils, their parents and siblings, as well as teachers and ...
A. Fontanet, L. Tondeur, Y. Madec, Rebecca Grant, C. Besombes, N. Jolly, S. Fernandes Pellerin, M. Ungeheuer, Isabelle Cailleau, Lucie Kuhmel, S. Temmam, C. Huon, Kuang-Yu Chen, B. Crescenzo, S. Munier, C. Demeret, L. Grzelak, I. Staropoli, T. Bruel, P. Gallian, S. Cauchemez, S. van der Werf, O. Schwartz, M. Eloit, B. Hoen   +24 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Real-world management and survival outcomes of patients with newly diagnosed gliomas from a single institution in China: A retrospective cohort study

Glioma, 2019
Background and Aim: Guidelines recommend adjuvant treatment for patients with high-grade gliomas and low-grade gliomas with high risk of progression. In clinical practice, however, treatments may not conform to these suggested guidelines.
Depei Li, Yinsheng Chen, Chengcheng Guo, Xiangheng Zhang, Ke Sai, Chao Ke, Ji Zhang, Xiaobing Jiang, Zhenghe Chen, Fuhua Lin, Qunying Yang, Jian Wang, Yonggao Mu, Zhongping Chen   +13 more
doaj   +1 more source