Results 81 to 90 of about 33,361,489 (319)

Factors associated with deaths by tuberculosis in the state of Mato Grosso, 2011-2020: retrospective cohort study [PDF]

Epidemiologia e Serviços de Saúde
Objective: To investigate factors associated with tuberculosis deaths in Mato Grosso state, Brazil, from 2011 to 2020. Methods: Retrospective cohort study with data obtained from the Notifiable Health Conditions Information System and the Mortality ...
Vanessa da Silva Lopes, Rodrigo de Macedo Couto, Alexandre Peron da Luz, Pãmela Rodrigues de Souza Silva, Jaqueline Costa Lima   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Coping is excellent in Swiss Children with inflammatory bowel disease: Results from the Swiss IBD cohort study [PDF]

, 2014
BACKGROUND: Inflammatory bowel disease (IBD) starting during childhood has been assumed to impair quality of life (QoL) of affected children. As this aspect is crucial for further personality development, the health-related quality of life (HRQOL) was ...
Spalinger, J., Heyland, Klaas, Rogler, Gerhard, Schibli, S., Braegger, C.P., Koller, R., Pittet, Valérie, Schäppi, Michela, Rueger, V., Koller, Rebekka, Rogler, G., Herzog, Denise, Bühr, P., Herzog, D., Bühr, Patrick, Friedt, Michael, Friedt, M., Rueger, Vanessa, Braegger, Christian P, Schibli, Susanne, Nydegger, Andreas, Rogler, Daniela, Nydegger, A., Pittet, V., Spalinger, Johannes, Fournier, N., Schäppi, M., Fournier, Nicolas, Rogler, D., Heyland, K.   +29 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Impact of Scotland's smoke-free legislation on pregnancy complications: retrospective cohort study [PDF]

, 2012
<b>Background:</b> Both active smoking and environmental tobacco smoke exposure are associated with pregnancy complications. In March 2006, Scotland implemented legislation prohibiting smoking in all wholly or partially enclosed public ...
Mackay Daniel F., Haw, S.J., Nelson Scott M., Pell, J.P., Pell, Jill, Mackay, D.F., Jill P Pell, Nelson, Scott M, Daniel F Mackay, Nelson, S.M., Pell Jill P., Mackay, Daniel F, Sally J Haw, Haw, Sally, Haw Sally J., Scott M Nelson   +15 more
core   +2 more sources

Methadone and perinatal outcomes: a retrospective cohort study [PDF]

American Journal of Obstetrics and Gynecology, 2011
The purpose of this study was to examine the relationship among methadone maintenance treatment, perinatal outcomes, and neonatal abstinence syndrome.This was a retrospective cohort study of 61,030 singleton births at a large maternity hospital from 2000-2007.There were 618 (1%) women on methadone at delivery.
Brian J, Cleary, Jean M, Donnelly, Judith D, Strawbridge, Paul J, Gallagher, Tom, Fahey, Martin J, White, Deirdre J, Murphy   +6 more
openaire   +2 more sources

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Fibromigraine: A cohort study retrospective

Headache Medicine
ObjectivesTo diagnose fibromyalgia in patients with migraine and assess the quality of life of these patients. Patients and MethodsA prospective, cross-sectional study was carried out, comparing groups, in a non-randomized sample, consisting of patients diagnosed with migraine.
Yasmine Maria Leódido-Fortes, Wallyson Pablo de Souza, Adriana Soares, Raimundo Silva-Néto   +3 more
openaire   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source