Results 71 to 80 of about 3,148,432 (179)

The iscom structure as an immune enhancing moiety: experience with viral systems. [PDF]

, 1992
Review ...
Carlson, Dalsgaard, De Vries, De Vries, De Vries, Ertürk, Fekadu, Horzinek, Howard, Höglund, Jones, Kensil, Kersten, Lövgren, Lövgren, Lövgren, Lövgren, McAleer, McGhee, Merza, Merza, Morein, Morein, Morgan, Mowat, Mowat, Nagy, Osterhaus, Osterhaus, Osterhaus, Osterhaus, Putkonen, Pyle, Scott, Sjölander, Speijers, Sundquist, Takahashi, Thapar, Trudel, Trudel, Trudel, Trudel, Tsuda, Ulaeto, Varsanyi, Visser, Wahren, Watson, Weiss, Winter, Yewdell, Åkerblom, Överness, Özel   +54 more
core   +2 more sources

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy [PDF]

, 2018
G-quadruplexes (G4s) are non-canonical nucleic acids secondary structures that form within guanine-rich strands of regulatory genomic regions. G4s have been extensively described in the human genome, especially in telomeres and oncogene promoters; in ...
Richter, Sara N, Ruggiero, Emanuela
core   +1 more source

Using Vesicular Stomatitis Virus as a Platform for Directed Protease Evolution

Current Protocols, Volume 4, Issue 12, December 2024.
Abstract Antiviral drugs are essential medications to save the lives of infected people. However, they are under constant threat to become ineffective as viruses evolve quickly. Studying the development of resistance is therefore paramount to understand the impact of mutations on pharmacological treatment and to make informed decisions.
Francesco Costacurta, Stefanie Rauch, Dorothee von Laer, Emmanuel Heilmann   +3 more
wiley   +1 more source

Anti-HIV/AIDS Drugs: An Overview

Journal of Drug Delivery and Therapeutics, 2019
Human Immunodeficiency Virus (HIV) is an enveloped virus, belonging to the viral family Retroviridae. It is a highly evolved virus which has grasped the attention of all researchers with its special features like morphology, genetics and also by its ...
Sonali Pawar, Santosh Waghmare, Bhagyashri Gawde, Pranit Kale, Yash Johri   +4 more
semanticscholar   +1 more source

Pseudotypes: your flexible friends [PDF]

, 2014
Pseudotype viruses: applications and troubleshooting' (EuroSciCon 2013), a 1-day conference held at Cineworld: The O2 (London, UK) on 2 October 2013, focused on the technique of pseudotyping enveloped viruses (for a review of the technique, see [1]). The
Daly, Janet M., King, Barnabas
core   +2 more sources

CRISPR/Cas9 Ribonucleoprotein Nucleofection for Genome Editing in Primary Human Keratinocytes: Knockouts, Deletions, and Homology‐Directed Repair Mutagenesis

Current Protocols, Volume 4, Issue 11, November 2024.
Abstract Keratinocytes are the most abundant cell type in the human epidermis, the outermost layer of the skin. For years, primary human keratinocytes (HKs) have been used as a crucial tool for studying the pathogenesis of a wide range of skin‐related diseases.
Martina Bamundo, Sara Palumbo, Ludovica D'Auria, Caterina Missero, Daniela Di Girolamo   +4 more
wiley   +1 more source

Vesicular Stomatitis Virus as a Platform for Protease Activity Measurements

Current Protocols, Volume 4, Issue 11, November 2024.
Abstract Protease inhibitors are among the most powerful antiviral drugs. They have been used successfully against viruses, such as the human immunodeficiency virus (HIV), hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Stefanie Rauch, Francesco Costacurta, Dorothee von Laer, Emmanuel Heilmann   +3 more
wiley   +1 more source

Characterization of the longitudinal HIV-1 quasispecies evolution in HIV-1 infected individuals co-infected with Mycobacterium tuberculosis [PDF]

, 2010
One of the earliest and most striking observations made about HIV is the extensive genetic variation that the virus has within individual hosts, particularly in the hypervariable regions of the env gene which is divided into 5 variable regions (V1-V5 ...
Leulebirhan, Tsigereda Biru
core  

DF-1-Derived exosomes mediate transmission of reticuloendotheliosis virus and resist REV-specific antibodies

Virology Journal
Background Reticuloendotheliosis virus (REV), a member of the family Retroviridae, is a hot area of research, and a previous study showed that exosomes purified from REV-positive semen were not blocked by REV-specific neutralizing antibodies and ...
Zhen Wang, Huizhen Cui, Yawen Zhang, Wanli Sun, Wenjie Yang, Peng Zhao   +5 more
doaj   +1 more source

The Unique Immune System of Bats: An Evolutionary Analysis and Bibliometric Study

Ecology and Evolution, Volume 14, Issue 11, November 2024.
Through the evolutionary and bibliometric analyses, this study identified several critical immune genes and signaling pathways related to bat immunity. Currently, research on the immune system of bats primarily focuses on the themes of “efficient antiviral responses” and “inflammation suppression.” ABSTRACT Bats exhibit a greater capacity to tolerate ...
Rui Li, Wenliang Zhao, Apeng Chen, Zhiqiang Wu, Gejing De   +4 more
wiley   +1 more source