Results 111 to 120 of about 84,233 (235)

Interactions between Retroviruses and the Host Cell Genome

Molecular Therapy: Methods & Clinical Development, 2017
Replication-defective retroviral vectors have been used for more than 25 years as a tool for efficient and stable insertion of therapeutic transgenes in human cells.
Valentina Poletti, F. Mavilio
semanticscholar   +1 more source

Development of the abdominal musculature in the chicken embryo

Journal of Anatomy, EarlyView.
In this study, we investigate anatomy, morphogenesis, segmental origin, and fiber formation of the abdominal musculature in the chicken embryo. We show that abdominal muscles arise from somites 24 to 28, and that the segmental identity of individual fibers in the abdominal muscle sheets is maintained.
Margarethe Draga, Luke Orth, Julia Khabyuk, Vanessa Holtwick, Johanna Heinen, Felicitas Pröls, Martin Scaal   +6 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

A Natural LTR Retrotransposon Insertion in the Promoter of GhNAC140‐Dt Boosts Cotton Lint Yield

Plant Biotechnology Journal, EarlyView.
ABSTRACT Transposable elements (TEs) are fundamental drivers of crop evolution and domestication. Whereas the underlying mechanisms of TE‐mediated gene activation remain poorly understood. Lint percentage is an important yield component in cotton. Here, we report a retrotransposon insertion in the promoter of GhNAC140‐Dt, a secondary wall NAC encoding ...
Yujia Yu, Xiaoguang Shang, Haitang Wang, Lijie Zhu, Xu Han, Qingfei He, Weixi Li, Yonglin Tan, Guozhong Zhu, Wangzhen Guo   +9 more
wiley   +1 more source

dNTP depletion and beyond: the multifaceted nature of SAMHD1-mediated viral restriction

Journal of Virology
SAMHD1 is a dNTPase of mammalian cells. In 2011, SAMHD1 was found to be a host restriction factor against retroviruses through dNTP reduction. Recent research provides evidence that the antiviral mechanisms of SAMHD1 cannot be explained solely by its ...
Pak-Hin Hinson Cheung, Hua Yang, Li Wu
doaj   +1 more source

Xenotransplantation at a Crossroads: Breakthroughs, Challenges, and the Path Forward

Organ Medicine, EarlyView.
Xiaoyu Gan, Jizhang Yu, Jie Wu, Junjie Zong   +3 more
wiley   +1 more source

Electromechanical modelling and simulation of human‐induced pluripotent stem cell‐derived cardiomyocytes predict drug‐induced contractility effects

The Journal of Physiology, EarlyView.
Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite, Xin Zhou, Andreas Koschinski, Wan‐Hua Hong, Marilù Casini, Manuel Koch, Ursula Ravens, Remi Peyronnet, Manuela Zaccolo, Blanca Rodriguez   +9 more
wiley   +1 more source

Evaluation of bovine leukaemia virus infection control measures in Japanese Black beef cattle breeding farms: A 7‐year longitudinal study based on proviral load

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Bovine leukaemia virus (BLV) infection remains a major problem for Japanese Black (Wagyu) cattle, and effective and sustainable control measures are essential to prevent its spread in breeding herds. This study aimed to monitor the BLV infection status of all cattle at a Japanese Black breeding farm in Kagoshima Prefecture, Japan ...
Makoto Kajisa, Chikako Tani, Mineto Tani, Jiazhou Li, Satoshi Ito, Takenori Yamauchi, Hironobu Murakami, Hiromu Katamoto, Reiichiro Sato, Shingo Nakahata   +9 more
wiley   +1 more source

Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Eaftekhar Ahmed Rana, Mahfuza Akther, Susan Beetson, Subir Sarker, Gabriele Rossi, Jasim M. Uddin   +5 more
wiley   +1 more source

Futures of Everyday Life: A Qualitative Content Analysis of Future Personas in Scenarios

FUTURES &FORESIGHT SCIENCE, Volume 8, Issue 1, April 2026.
ABSTRACT Scenario reports, holding a long‐standing tradition in foresight and futures studies, act as an essential document for organizations to prepare for possible, plausible, and alternative futures. Focusing on descriptions and representations of everyday life, we examined 29 future persona narratives from six publications—covering a wide field ...
Gerhard Schönhofer, Pauli Komonen, Jan Oliver Schwarz, Laura Bechthold   +3 more
wiley   +1 more source