Results 111 to 120 of about 120,627 (303)
Precise Therapy Using the Selective Endogenous Encapsidation for Cellular Delivery Vector System
PharmaceuticsInterindividual variability in drug response is a major problem in the prescription of pharmacological treatments. The therapeutic effect of drugs can be influenced by human genes.
Vacis Tatarūnas +2 more
doaj +1 more source
HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear
Viruses, 2010 HIV-1 transcription is regulated at the level of elongation by the viral Tat protein together with the cellular elongation factor P-TEFb, which is composed of cyclin T1 and Cdk9 subunits.
Alan D. Frankel, Iván D’Orso
doaj +1 more source
Understanding the process of envelope glycoprotein incorporation into virions in simian and feline immunodeficiency viruses [PDF]
, 2014 The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis.
Affranchino, Jose Luis +1 more
core +4 more sources
Approaches to repurposing reverse transcriptase antivirals in cancer
British Journal of Clinical Pharmacology, EarlyView.This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head +2 more
wiley +1 more source
Increasing the scope and intensity of interventions to prevent HIV infection in infants: Best interests of women and children. [PDF]
, 2007 A
Chersich, Matthew +2 more
core +1 more source
Investigating the role of SARM1 in central nervous system
Ibrain, EarlyView.Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1) is a pivotal molecule that has garnered extensive attention in neuroscience. As an intracellular molecule, SARM1 possesses various crucial biological functions in the nervous system.
Junjie Wang +4 more
wiley +1 more source
iMetaOmics, EarlyView.This study built a Wenchang chicken haplotype genome and integrated it with 29 others to create a chicken pangenome atlas. Analysis of 354 chickens revealed 185,205 structural variations (SVs), with one‐third derived from homology‐based and transposable elements.
Lihong Gu +9 more
wiley +1 more source
iMeta, EarlyView.Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang +12 more
wiley +1 more source
Inhibition of viral DNA synthesis in stationary chicken embryo fibroblasts infected with avian retroviruses [PDF]
, 1977 Edward F. Fritsch, Howard M. Temin
openalex +1 more source
Bee products as alternatives in the treatment of viral infections
Journal of the Science of Food and Agriculture, EarlyView.Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source