Results 131 to 140 of about 120,627 (303)

Circulating Cell‐Free DNA of Bovine Leukemia Virus: A Promising Biomarker for Enzootic Bovine Leukosis

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT Bovine leukemia virus (BLV) causes Enzootic bovine leukosis (EBL) in approximately 1%–5% of infected cattle after a long latent period. Few biomarkers effectively distinguish non‐EBL from EBL cattle. Given the rapid turnover of tumor cells, we hypothesized that cell‐free DNA (cfDNA) in plasma could serve as a more effective biomarker for EBL ...
M. Ishrat Jahan   +11 more
wiley   +1 more source

Reply to: Lack of evidence for involvement of known human retroviruses in multiple sclerosis [PDF]

open access: bronze, 1986
Hilary Koprowski   +8 more
openalex   +1 more source

Anti‐Human Endogenous Retrovirus and Anti‐Myelin Oligodendrocyte Glycoprotein Humoral Response in Cerebrospinal Fluid of Multiple Sclerosis Patients: A Case Control Study

open access: yesMicrobiology and Immunology, EarlyView.
ABSTRACT It is believed that human endogenous retrovirus (HERV)‐W plays a fundamental role in multiple sclerosis (MS) pathogenesis, probably by inducing humoral and cellular immunopathological response. HERVs present regions of similarity to myelin oligodendrocyte glycoprotein (MOG) and therefore could induce autoimmunity through the mechanism of ...
Karin C. Garcia   +11 more
wiley   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Endogenous Viral Etiology of Prion Diseases [PDF]

open access: yes, 2009
Transmissible spongiform encephalopathies (TSEs), or prion diseases, are a group of incurable neurodegenerative disorders, including Kuru and Creutzfeldt-Jakob disease in humans, “mad cow” disease in cattle, and scrapie in sheep. This paper
Claudiu I. Bandea
core   +1 more source

Age and Sex Effects on Blood Retrotransposable Element Expression Levels: Findings From the Population‐Based Rhineland Study

open access: yesAging Cell, EarlyView.
Retrotransposable element (RTE) expression increases with chronological and biological age and is negatively associated with heterochromatin regulators. Moreover, RTE expression shows sex‐specific differences, with higher levels in men and enrichment for immune‐related pathways.
Valentina Talevi   +6 more
wiley   +1 more source

Comparison of the generic neuronal differentiation and neuron subtype specification functions of mammalian achaete-scute and atonal homologs in cultured neural progenitor cells [PDF]

open access: yes, 2002
In the vertebrate peripheral nervous system, the proneural genes neurogenin 1 and neurogenin 2 (Ngn1 and Ngn2), and Mash1 are required for sensory and autonomic neurogenesis, respectively.
Anderson, David J.   +3 more
core  

hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan

open access: yesAging Cell, EarlyView.
In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam   +15 more
wiley   +1 more source

Prognostic factors in bushfire‐affected koalas–Kangaroo Island bushfire response 2020

open access: yesAustralian Veterinary Journal, EarlyView.
This study presents a retrospective analysis of clinical records data from koalas presenting for treatment following the large‐scale bushfire event on Kangaroo Island 2019–2020. The aim of the study was to identify prognostic factors for koalas affected by bushfire. Koalas (n = 199) were grouped based on their burn status in combination with their burn
O Funnell   +6 more
wiley   +1 more source

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