Results 141 to 150 of about 124,737 (275)
Cell and Gene Therapy in Equine Ocular Disease
ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Kimberly A. S. Young +2 more
wiley +1 more source
Is it currently possible to evaluate the risk posed by PERVs for clinical xenotransplantation? [PDF]
Denner, Joachim +2 more
core +1 more source
Analysis of the impact of TRIM5 polymorphism on retroviral replication [PDF]
This project aims to improve the SIV/rhesus macaques animal model for AIDS. TRIM5α is an antiviral molecule expressed in mammals including rhesus macaques.
Maplanka, Charlotte
core
Integrated scFv identification and CAR T cell generation for AML targeting in vivo
What's new? Acute myeloid leukemia (AML) is a rapidly progressing blood cancer. Advancing chimeric antigen receptor (CAR) T cell therapies, particularly through rapid translation of single chain variable fragment (scFv) discovery into CAR constructs, may improve clinical outcomes, especially the development of patient individualized CAR T cells.
Yi Liu +13 more
wiley +1 more source
Classification of Retroviruses Based on Genomic Data Using RVGC
Khalid Mahmood Aamir +5 more
openalex +1 more source
Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias
Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei +32 more
wiley +1 more source
ABSTRACT Advancing reproductive technologies in livestock is essential to improve both productivity and genetic potential of cattle. Despite this importance, application of reproductive biotechnologies in cattle breeding remains limited. Bovine granulosa cells (bGCs), which are key components of the ovarian follicle, are critical in female reproduction
Lanlan Bai +12 more
wiley +1 more source
UL induced significant spatial and non‐spatial cognitive dysfunction and hippocampal neurogenesis inhibition, whereas aerobic exercise intervention effectively reversed these impairments. Transcriptomic profiling and pharmacological evidence identified MHC class I/II–related pathways (H2‐K1, H2‐Eb1, CD74) as key mediators of the restorative effects of ...
Zhanghong Zhou +13 more
wiley +1 more source
Evolution and Distribution of Class II-Related Endogenous Retroviruses
Robert J. Gifford +4 more
openalex +1 more source

